CISD2

Gene Symbol CISD2
Entrez Gene 493856
Alt Symbol ERIS, Miner1, NAF-1, WFS2, ZCD2
Species Human
Gene Type protein-coding
Description CDGSH iron sulfur domain 2
Other Description CDGSH iron-sulfur domain-containing protein 2|endoplasmic reticulum intermembrane small protein|mitoNEET-related 1 protein|nutrient-deprivation autophagy factor-1|zinc finger, CDGSH-type domain 2
Swissprots Q7Z3D5 Q8N5K1
Accessions EAX06148 EAX06149 Q8N5K1 AA424361 AI277147 AK292134 BAF84823 AM392809 CAL37687 AM393385 CAL38263 BC020831 BC032300 AAH32300 BX537971 CAD97935 DB351048 DB565768 DN993861 NM_001008388 NP_001008389
Function Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy. {ECO:0000269|PubMed:17846994, ECO:0000269|PubMed:20010695}.
Subcellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane; Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum. However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane.
Tissue Specificity Testis, small intestine, kidney, lung, brain, heart, pancreas and platelets. {ECO:0000269|PubMed:17846994}.

ERIS CRISPR/Cas9 KO Plasmid (h) - sc-416072 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS HDR Plasmid (h) - sc-416072-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS Double Nickase Plasmid (h) - sc-416072-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS Double Nickase Plasmid (h2) - sc-416072-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS CRISPR Activation Plasmid (h) - sc-416072-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS CRISPR Activation Plasmid (h2) - sc-416072-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS Lentiviral Activation Particles (h) - sc-416072-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS Lentiviral Activation Particles (h2) - sc-416072-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ERIS siRNA (h) - sc-89146 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERIS shRNA Plasmid (h) - sc-89146-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ERIS shRNA (h) Lentiviral Particles - sc-89146-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU143591 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6141 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6141 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

CISD2 siRNA (Human) - CRJ8357 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CISD2 - MBS8234006 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CISD2 (NM_001008388.4) - SHH264193 from Creative biogene

Category siRNA
Species Reactivities Human

Human CISD2 siRNA - orb278858 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CISD2 shRNA Plasmid (Human) - CHJ8357 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CISD2 miRNA 3'UTR clone - MiUTR3H-11938 from Creative biogene

Species Reactivities Human
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