KLKB1

Gene Symbol KLKB1
Entrez Gene 3818
Alt Symbol KLK3, PPK
Species Human
Gene Type protein-coding
Description kallikrein B, plasma (Fletcher factor) 1
Other Description Fletcher factor|kininogenin|plasma kallikrein|plasma kallikrein heavy chain|plasma kallikrein light chain|plasma prekallikrein
Swissprots Q4W5C3 Q17RE8 A6NH96 B2R8H9 P03952 Q17RE9
Accessions AAF79940 AAN84794 AAY40900 EAX04622 EAX04623 P03952 AK292624 BAF85313 AK297672 BAG60034 AK313378 BAG36176 AW182528 BC117349 AAI17350 BC117351 AAI17352 BC143911 CN265612 HQ258334 ADR83088 M13143 AAA60153 XM_011531930 XP_011530232 XM_011531931 XP_011530233 XM_011531932 XP_011530234 XM_011531933 XP_011530235 XM_011531934 XP_011530236 NM_000892 NP_000883
Function The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Subcellular Location Secreted.
Top Pathways Complement and coagulation cascades

Kininogen HC (H-70) - sc-25799 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Kininogen HC (H-70): sc-25799. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in glomeruli and tubuli at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

plasma kallikrein (T-19) - sc-18659 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
plasma kallikrein (T-19): sc-18659. Western blot analysis of plasma kallikrein expression in mouse plasma tissue extract.

plasma kallikrein (H-57) - sc-367705 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
plasma kallikrein (H-57): sc-367705. Western blot analysis of plasma kallikrein expression in K-562 whole cell lysate.

plasma kallikrein (G-20) - sc-18658 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

plasma kallikrein (H-25) - sc-133915 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
plasma kallikrein (H-25): sc-133915. Western blot analysis of plasma kallikrein expression in human fetal liver tissue extract.

Anti-Plasma Kallikrein 1B antibody - ab196555 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Plasma Kallikrein 1B antibody (ab196555) at 1/500 dilutionLane 1 : Mouse liver extractLane 2 : Mouse intestine extractLane 3 : Mouse brain extract

Anti-Plasma Kallikrein 1B antibody - ab44392 from Abcam

Prices $387.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab44392 staining Kallikrein 1B in human temporal neocortical tissue sections IHC-P . Tissue samples were fixed with formaldehyde and blocked with 10% serum for 20 minutes at 23°C: antigen retrieval was performed by heat mediation in citrate buffer.. Samples were incubated with primary antibody (1/100) for 18 hours at 23°C . A biotin-conjugated horse anti Rabbit IgG  polyclonal (1/50) was used as secondary antibody.See Abreview

Anti-Plasma Kallikrein 1B antibody - ab43084 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Plasma Kallikrein 1B antibody - ab44203 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Plasma Kallikrein 1B antibody - ab75228 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Plasma Kallikrein 1B antibody (ab75228) at 1/500 dilutionLane 1 : Extracts from HeLa cellsLane 2 : Extracts from HeLa cells with Cl peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-Plasma Kallikrein 1B antibody - ab116517 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Plasma Kallikrein 1B antibody (ab116517) at 1/100 dilution + K562 cell line lysate at 35 µg

Anti-Plasma Kallikrein 1B antibody [13G11] - ab1006 from Abcam

Prices $392.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 13G11
developed using the ECL techniquePerformed under reducing conditions.Exposure time : 2 minutesThis image is courtesy of an anonymous AbreviewSee Abreview

Anti-Plasma Kallikrein 1B antibody [EPR5707] - ab124938 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5707
ab124938, at 1/50 dilution, staining Plasma Kallikrein 1B in paraffin-embedded Human kidney tissue by Immunohistochemistry.

Anti-KLKB1 / Plasma Kallikrein Antibody (aa20-638) - LS-C37114 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rat
Clonality Monoclonal

Anti-KLKB1 / Plasma Kallikrein Antibody (clone 13G11) - LS-C83337 from LifeSpan Bioscience

Prices $475.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone 13G11

Anti-KLKB1 / Plasma Kallikrein Antibody (clone 13G11) - LS-C38308 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 13G11

Anti-KLKB1 / Plasma Kallikrein Antibody - LS-C130321 from LifeSpan Bioscience

Prices $405.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-KLKB1 / Plasma Kallikrein Antibody - LS-C185168 from LifeSpan Bioscience

Prices $495.00
Sizes 1 ml
Host Goat
Clonality Polyclonal

Anti-KLKB1 / Plasma Kallikrein Antibody (aa507-537, AP) - LS-C261488 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLKB1 / Plasma Kallikrein Antibody (aa507-537, APC) - LS-C261489 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLKB1 / Plasma Kallikrein Antibody (aa507-537, FITC) - LS-C261490 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLKB1 / Plasma Kallikrein Antibody (aa507-537, Biotin) - LS-C261491 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLKB1 / Plasma Kallikrein Antibody (aa507-537, PE) - LS-C261493 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KLKB1 / Plasma Kallikrein Antibody (C-Terminus) - LS-C135182 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KLKB1 antibody LS-C135182 Western blot of Rat Brain lysate. Antibody concentration 1 ug/ml.

Anti-KLKB1 / Plasma Kallikrein Antibody (aa429-478) - LS-C80752 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Fetal liver cell lysate. Antibody concentration: 2.5 ug/ml. Gel concentration: 12%.
Search more