KLKB1

Gene Symbol	KLKB1
Entrez Gene	3818
Alt Symbol	KLK3, PPK
Species	Human
Gene Type	protein-coding
Description	kallikrein B, plasma (Fletcher factor) 1
Other Description	Fletcher factor|kininogenin|plasma kallikrein|plasma kallikrein heavy chain|plasma kallikrein light chain|plasma prekallikrein
Swissprots	Q4W5C3 Q17RE8 A6NH96 B2R8H9 P03952 Q17RE9
Accessions	AAF79940 AAN84794 AAY40900 EAX04622 EAX04623 P03952 AK292624 BAF85313 AK297672 BAG60034 AK313378 BAG36176 AW182528 BC117349 AAI17350 BC117351 AAI17352 BC143911 CN265612 HQ258334 ADR83088 M13143 AAA60153 XM_011531930 XP_011530232 XM_011531931 XP_011530233 XM_011531932 XP_011530234 XM_011531933 XP_011530235 XM_011531934 XP_011530236 NM_000892 NP_000883
Function	The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Plasma Kallikrein 1B full length protein - ab77870 from Abcam Category Protein Prices $356.00 Sizes 50 µg Source Native Species Human

Active mouse Plasma Kallikrein 1B full length protein - ab185261 from Abcam Category Protein Prices $721.00 Sizes 100 µg Source Insect cells Species Mouse

Human Plasma Kallikrein 1B full length protein - ab187005 from Abcam Category Protein Source Native Species Human

Plasma Kallikrein 1B peptide - ab43117 from Abcam Category Peptide

Plasma Kallikrein 1B peptide - ab43118 from Abcam Category Peptide

Plasma Kallikrein 1B peptide - ab43119 from Abcam Category Peptide

KLKB1 / Plasma Kallikrein Antibody Blocking Peptide - LS-E2978 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Plasma Kallikrein/KLKB1 Protein - NBP2-12555 from Novus Biologicals Category Protein Prices $309.00 Sizes 50 µg Species Human

KLKB1-Antibody-C-term-Blocking-peptide - BP14109b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Plasma Kallikrein/KLKB1, CF - 2497-SE-010 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Gly20-Ala638, with a C-terminal 6-His tag

Recombinant rat Plasma kallikrein (OPCA00147) - OPCA00147 from Aviva Systems Biology Category Protein Prices $220.00 Sizes 50 µg Species Rat

Purified Plasma Kallikrein Protein (OPMA04258) - OPMA04258 from Aviva Systems Biology Category Protein Prices $140.00 Sizes 50 µg Source Human Plasma

PPK Protein (OPPA00788) - OPPA00788 from Aviva Systems Biology Category Protein Prices $1,170.00 Sizes 50 iu Source Propionibacterium shermanii

Kallikrein protein - 30R-2456 from Fitzgerald Category Protein Prices $255.00 Sizes 50 µg

Klkb1 Blocking Peptide - 33R-3476 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Plasma Kallikrein Protein - abx060944 from Abbexa Category Protein Source Human Plasma

KLKB1 / Kininogen - BA371 from Acris Antibodies Category Protein Prices $205.00 Sizes 50 µg Source Plasma Species Human

Polyphosphate Kinase (PPK) - 12-4303 from ARP American Research Products Category Protein Prices $699.00 Sizes 50 iu Source Recombinant, Propionibacterium shermania

Recombinant Human Kallikrein B, Plasma (Fletcher factor) 1, His-tagged - KLKB1-483H from Creative Biomart Category Protein Source Murine myeloma cellline, NS0-derived

Native Human KLKB1 - KLKB1-27924TH from Creative Biomart Category Protein Species Human

Native Human Kallikrein - KLKB1-210H from Creative Biomart Category Protein Source Human Urine Species Human

Recombinant Prekallikrein (PK) - RPB801Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Prekallikrein, Human Plasma - 529583 from EMD Millipore Source Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. Species Human

Kallikrein, Human Plasma - 420307 from EMD Millipore Source Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. Species Human

Recombinant Prekallikrein (PK) - RPB801Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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