KLKB1

Gene Symbol	KLKB1
Entrez Gene	3818
Alt Symbol	KLK3, PPK
Species	Human
Gene Type	protein-coding
Description	kallikrein B, plasma (Fletcher factor) 1
Other Description	Fletcher factor|kininogenin|plasma kallikrein|plasma kallikrein heavy chain|plasma kallikrein light chain|plasma prekallikrein
Swissprots	Q4W5C3 Q17RE8 A6NH96 B2R8H9 P03952 Q17RE9
Accessions	AAF79940 AAN84794 AAY40900 EAX04622 EAX04623 P03952 AK292624 BAF85313 AK297672 BAG60034 AK313378 BAG36176 AW182528 BC117349 AAI17350 BC117351 AAI17352 BC143911 CN265612 HQ258334 ADR83088 M13143 AAA60153 XM_011531930 XP_011530232 XM_011531931 XP_011530233 XM_011531932 XP_011530234 XM_011531933 XP_011530235 XM_011531934 XP_011530236 NM_000892 NP_000883
Function	The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Subcellular Location	Secreted.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-KLKB1-cDNA-Clone - DC14054 from Abgent, a WuXi AppTec company Prices $861.30 Sizes 10 µg Species Human Accession BC117351

KLKB1 - MBS1268383 from MyBioSource Species Human Accession BC117349

KLKB1 - MBS1266888 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC117351

Human KLKB1 ORF clone(NM_000892.3) - CDCL185060 from Creative Biomart Species Human Accession NM_000892.3

Human KLKB1 ORF Clone(NM_000892.3) - CDCL168243 from Creative Biomart Species Human Accession NM_000892.3

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone in cloning vector - HG10311-G from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10311-NY from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, C-His tag - HG10311-CH from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10311-NH from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10311-CM from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG10311-ACG from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG10311-ACR from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid - HG10311-UT from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG10311-CY from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG10311-NF from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG10311-NM from Sino Biological Species Human

Human Kallikrein 1B/KLKB1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10311-CF from Sino Biological Species Human

Human KLKB1 ORF clone(NM_000892.3) - CDCL185060 from Creative biogene Species Human

Human KLKB1 ORF Clone (BC117351) - CDCS405977 from Creative biogene Species Human Accession P03952

Human KLKB1 ORF Clone (BC117349) - CDCS405978 from Creative biogene Species Human Accession P03952

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