PTDSS1

Gene Symbol	PTDSS1
Entrez Gene	9791
Alt Symbol	LMHD, PSS1, PSSA
Species	Human
Gene Type	protein-coding
Description	phosphatidylserine synthase 1
Other Description	PSS-1\|ptdSer synthase 1\|serine-exchange enzyme I
Swissprots	B4DE85 P48651 Q9BUQ5 E5RFC5
Accessions	EAW91753 EAW91754 P48651 AK293036 BAF85725 AK293513 BAG56996 BC002376 AAH02376 BC004192 AAH04192 BC004390 AAH04390 BC004502 AAH04502 BM459031 D14694 BAA03520 DQ891825 ABM82751 DQ895012 ABM85938 HY087183 NM_001290225 NP_001277154 NM_014754 NP_055569
Function	Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250}.
Top Pathways	Glycerophospholipid metabolism

PSS1 (Y-19) - sc-51410 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PSS1 (Y-19): sc-51410. Western blot analysis of PSS1 expression in mouse brain tissue extract.

PSS1 (H-172) - sc-134796 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 antibody - ab82642 from Abcam

Prices	$370.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 antibody (ab82642) at 1 µg/ml + 293T cell lysate at 10 µgSecondaryHRP-conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PTDSS1 antibody - ab130517 from Abcam

Prices	$370.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 antibody (ab130517) at 1/100 dilution + MDA-MB453 cell line lysate at 35 µg

Anti-PTDSS1 antibody - ab69951 from Abcam

Prices	$370.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

All lanes : Anti-PTDSS1 antibody (ab69951) at 1/500 dilutionLane 1 : PTDSS1 transfected 293T cell lysateLane 2 : non transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-PTDSS1 antibody [EPR8118(2)] - ab157222 from Abcam

Prices	$357.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EPR8118(2)

Immunoprecipitation : 293T cell lysate immunoprecipitated with ab157222 at 1/10Western Blot: ab157222 at 1/1000 labeling PTDSS1 in immunoprecipitation pellet from 293T cell lysateSecondary Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution

Anti-PTDSS1 Antibody (N-Terminus) - LS-C80986 from LifeSpan Bioscience

Host	Rabbit
Clonality	Polyclonal

293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PTDSS1 Antibody (aa389-418, APC) - LS-C284830 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody (aa389-418, AP) - LS-C284831 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody (aa389-418, FITC) - LS-C284832 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody (aa389-418, Biotin) - LS-C284833 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody (aa389-418, PE) - LS-C284834 from LifeSpan Bioscience

Prices	$545.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody (aa389-418) - LS-C324378 from LifeSpan Bioscience

Prices	$345.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody - LS-C211683 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western blot of Phosphatidylserine synthase 1 antibody at 2 ug/ml. Lane 1: EC109 whole cell lysate. Lane 2: 293T whole cell lysate. Secondary: Goat polyclonal to Rabbit IgG at 1:15000 dilution. Predicted band size: 52 kDa. Observed band size: 36 kDa.

Anti-PTDSS1 Antibody (aa389-418) - LS-C162267 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

PTDSS1 Antibody western blot of MDA-MB453 cell line lysates (35 ug/lane). The PTDSS1 antibody detected the PTDSS1 protein (arrow).

Anti-PTDSS1 Antibody (HRP) - LS-C211684 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody (FITC) - LS-C212330 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PTDSS1 Antibody (Biotin) - LS-C212331 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

PTDSS1 Antibody - NBP1-83060 from Novus Biologicals

Prices	$419.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunocytochemistry/Immunofluorescence: PTDSS1 Antibody [NBP1-83060] - Immunofluorescent staining of human cell line A-431 shows localization to endoplasmic reticulum.

PTDSS1 Antibody - NBP1-59966 from Novus Biologicals

Prices	$139.00, $329.00
Sizes	20 µl, 100 µl
Host	Rabbit
Clonality	Polyclonal

Western Blot: PTDSS1 Antibody [NBP1-59966] - 293T cells lysate, concentration 0.2-1 ug/ml.

PTDSS1 Antibody - H00009791-B01P from Novus Biologicals

Prices	$359.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

PTDSS1 Antibody - H00009791-D01P from Novus Biologicals

Prices	$399.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Western Blot: PTDSS1 Antibody [H00009791-D01P] - Analysis of PTDSS1 expression in transfected 293T cell line by PTDSS1 polyclonal antibody.Lane 1: PTDSS1 transfected lysate(55.50 KDa).Lane 2: Non-transfected lysate.

Anti-PTDSS1 antibody produced in rabbit - SAB1411695 from Sigma-Aldrich

Prices	$347.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-PTDSS1: <B>Cat. No. SAB1411695</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~55.5 kDa using PTDSS1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PTDSS1 antibody produced in mouse - SAB1406881 from Sigma-Aldrich

Prices	$347.00
Sizes	50 µg
Host	Mouse
Clonality	Polyclonal

<B>Immunoblotting</B><BR/>Anti-PTDSS1: <B>Cat. No. SAB1406881</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~52 kDa using PTDSS1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PTDSS1 antibody produced in rabbit - HPA016852 from Sigma-Aldrich

Prices	$429.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

<B>Immunohistochemistry</B><BR/>Anti-PTDSS1: <B>Cat. No. HPA016852</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney shows strong nuclear positivity in cells in renal tubules.

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