FADD

Gene Symbol	FADD
Entrez Gene	8772
Alt Symbol	GIG3, MORT1
Species	Human
Gene Type	protein-coding
Description	Fas (TNFRSF6)-associated via death domain
Other Description	FAS-associated death domain protein|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor induced toxicity|mediator of receptor-induced toxicity
Swissprots	Q14866 Q13158 Q6IBR4
Accessions	AAB58469 AAB58483 ABD96828 EAW74760 EAW74761 EAW74762 Q13158 AI886015 AK291005 BAF83694 AK293320 BAG56839 AL575732 AY423721 AAS00484 BC000334 AAH00334 BC025733 BT006927 AAP35573 CR456738 CAG33019 EU176185 ABW03636 U24231 AAA86517 X84709 CAA59197 NM_003824 NP_003815
Function	Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. {ECO:0000269|PubMed:16762833, ECO:0000269|PubMed:19118384, ECO:0000269|PubMed:20935634, ECO:0000269|PubMed:21109225}.
Tissue Specificity	Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Top Pathways	Chagas disease (American trypanosomiasis), TNF signaling pathway, Herpes simplex infection, Tuberculosis, Apoptosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Phospho-FADD (Ser194) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1130 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse Phospho-FADD (Ser191) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1754 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Human FADD ELISA Kit (Cell-Based ELISA) - LS-F1980 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Protein FADD (FADD), Human, ELISA Kit - CSB-EL007958HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

FADD (Human) Matched Antibody Pair - H00008772-AP11 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

FADD (Human) Matched Antibody Pair - H00008772-AP12 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

FADD (Human) Matched Antibody Pair - H00008772-AP51 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

FADD Colorimetric Cell-Based ELISA Kit - CB5254 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

FADD (Phospho-Ser194) Colorimetric Cell-Based ELISA Kit - CBP1114 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Fas (TNFRSF6) -associated via death domain, ELISA Kit - MBS913591 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 31.25 pg/ml. Range 125 pg/ml-8000 pg/ml.

Fadd, Human - DP-10066-X from Nordic BioSite

Human Protein FADD(FADD) ELISA kit - CSB-EL007958HU from Cusabio Category ELISA Kit Sensitivity 31.25 pg/ml Range 125 pg/ml-8000 pg/ml

FADD ELISA Kit - DEIA-XYA1012 from Creative Diagnostics Category ELISA Kit

FADD (Phospho-Ser194) ELISA Kit - DEIA-XYA962 from Creative Diagnostics Category ELISA Kit

Human Protein FADD (FADD) ELISA Kit - EKC35196 from Biomatik Category ELISA Kit Prices $705.00, $2,820.00, $5,288.00 Sizes 96 t, 5x96t, 10x96t Sensitivity 31.25 pg/ml Range 125 pg/ml-8000 pg/ml

Human FADD ELISA Kit - E014444 from Biobool Category ELISA Kit Sensitivity Typically less than 31.25 pg/ml

FADD ELISA Kit (Human) (OKCA00775) - OKCA00775 from Aviva Systems Biology Category ELISA Kit Prices $590.00 Sizes 96 wells Sensitivity 31.25 pg/mL Range 125 pg/mL-8,000 pg/mL

anti-FADD antibody - ARG65617 from Arigo Biolaboratories Category ELISA Kit

anti-FADD antibody - ARG54127 from Arigo Biolaboratories Category ELISA Kit

anti-FADD antibody [J1D2] - ARG56961 from Arigo Biolaboratories Category ELISA Kit

Human Protein FADD (FADD) ELISA Kit - AE61125HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.065 ng/mL Range 0.156-10 ng/mL

Fas Associating Death Domain Containing Protein (FADD) , ELISA Kit - MBS2088205 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of this kit is typically less than 0.065ng/mL. Range 0.156-10ng/mL

Human FADD ELISA Kit (Sandwich ELISA) - LS-F39094 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.065 Range 0.156-10 ng/ml

FADD Colorimetric Cell-Based ELISA Kit - EKA50215 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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