FADD

Gene Symbol FADD
Entrez Gene 8772
Alt Symbol GIG3, MORT1
Species Human
Gene Type protein-coding
Description Fas (TNFRSF6)-associated via death domain
Other Description FAS-associated death domain protein|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor induced toxicity|mediator of receptor-induced toxicity
Swissprots Q14866 Q13158 Q6IBR4
Accessions AAB58469 AAB58483 ABD96828 EAW74760 EAW74761 EAW74762 Q13158 AI886015 AK291005 BAF83694 AK293320 BAG56839 AL575732 AY423721 AAS00484 BC000334 AAH00334 BC025733 BT006927 AAP35573 CR456738 CAG33019 EU176185 ABW03636 U24231 AAA86517 X84709 CAA59197 NM_003824 NP_003815
Function Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. {ECO:0000269|PubMed:16762833, ECO:0000269|PubMed:19118384, ECO:0000269|PubMed:20935634, ECO:0000269|PubMed:21109225}.
Tissue Specificity Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Top Pathways Chagas disease (American trypanosomiasis), TNF signaling pathway, Herpes simplex infection, Tuberculosis, Apoptosis

FADD CRISPR/Cas9 KO Plasmid (h) - sc-400580 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD HDR Plasmid (h) - sc-400580-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD Double Nickase Plasmid (h) - sc-400580-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD Double Nickase Plasmid (h2) - sc-400580-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD CRISPR Activation Plasmid (h) - sc-400580-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD CRISPR Activation Plasmid (h2) - sc-400580-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD Lentiviral Activation Particles (h) - sc-400580-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD Lentiviral Activation Particles (h2) - sc-400580-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

FADD siRNA (h) - sc-35352 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FADD shRNA Plasmid (h) - sc-35352-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FADD shRNA (h) Lentiviral Particles - sc-35352-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

FADD RNAi - H00008772-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU024471 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1364 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1364 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07030 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr07030

FADD siRNA (Human) - CRH5777 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FADD - MBS8208999 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human FADD (NM_003824.3) - SHH288697 from Creative biogene

Category siRNA
Species Reactivities Human

Human FADD siRNA - orb266279 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

FADD shRNA Plasmid (Human) - CHH5777 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

FADD miRNA 3'UTR clone - MiUTR3H-05013 from Creative biogene

Species Reactivities Human
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