FADD

Gene Symbol	FADD
Entrez Gene	8772
Alt Symbol	GIG3, MORT1
Species	Human
Gene Type	protein-coding
Description	Fas (TNFRSF6)-associated via death domain
Other Description	FAS-associated death domain protein|Fas-associating death domain-containing protein|Fas-associating protein with death domain|growth-inhibiting gene 3 protein|mediator of receptor induced toxicity|mediator of receptor-induced toxicity
Swissprots	Q14866 Q13158 Q6IBR4
Accessions	AAB58469 AAB58483 ABD96828 EAW74760 EAW74761 EAW74762 Q13158 AI886015 AK291005 BAF83694 AK293320 BAG56839 AL575732 AY423721 AAS00484 BC000334 AAH00334 BC025733 BT006927 AAP35573 CR456738 CAG33019 EU176185 ABW03636 U24231 AAA86517 X84709 CAA59197 NM_003824 NP_003815
Function	Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. {ECO:0000269|PubMed:16762833, ECO:0000269|PubMed:19118384, ECO:0000269|PubMed:20935634, ECO:0000269|PubMed:21109225}.
Tissue Specificity	Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.
Top Pathways	Chagas disease (American trypanosomiasis), TNF signaling pathway, Herpes simplex infection, Tuberculosis, Apoptosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

FADD peptide - ab54083 from Abcam Category Peptide Prices $181.00 Sizes 50 µg

Human FADD full length protein - ab89242 from Abcam Category Protein Source E. coli Species Human

Human FADD full length protein - ab88397 from Abcam Category Protein Source E. coli Species Human

FADD Antibody Blocking Peptide - LS-E10551 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FADD Antibody Blocking Peptide - LS-E10569 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FADD Antibody Blocking Peptide - LS-E6737 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FADD Antibody Blocking Peptide - LS-E7271 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FADD Partial Recombinant Protein - H00008772-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human FADD Protein - H00008772-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human FADD Protein - NBP1-30266 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

Recombinant Human FADD Protein - NBC1-18513 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E.coli Species Human

FADD-AntibodyCenter-Blocking-peptide - BP19607c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

FADD Protein - GTX110546-pro from GeneTex Category Protein Prices $299.00 Sizes 25 μg Source E. coli Species Human

FADD Protein (OPPA02124) - OPPA02124 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 2 µg Source E. Coli

Human FADD protein - orb81113 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Species Human

FADD Peptide - orb224247 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human

FADD Blocking Peptide - 33R-10607 from Fitzgerald Category Peptide Prices $145.00 Sizes 50 µg

FADD Blocking Peptide - 33R-1537 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FADD Blocking Peptide - 33R-1252 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

FADD protein (His tag) - 80R-1206 from Fitzgerald Category Protein Prices $340.00 Sizes 50 µg Source E.coli

Human FADD Protein - abx066498 from Abbexa Category Protein Source E.coli Species Human

FADD (1-208, His-tag) - AR09290PU-L from Acris Antibodies Category Protein Prices $1,020.00 Sizes 250 µg Source E. coli Species Human

FADD (1-208, His-tag) - AR09290PU-N from Acris Antibodies Category Protein Prices $420.00 Sizes 50 µg Source E. coli Species Human

FADD - H00008772-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FADD - H00008772-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

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