RNASE3

Gene Symbol	RNASE3
Entrez Gene	6037
Alt Symbol	ECP, RNS3
Species	Human
Gene Type	protein-coding
Description	ribonuclease, RNase A family, 3
Other Description	RNase 3|cytotoxic ribonuclease|eosinophil cationic protein|ribonuclease 3
Swissprots	Q4VBC1 P12724 Q8WZ62 Q9GZN9 Q8WTP7
Accessions	AAG31589 AAG31590 AAG31591 AAG31592 AAG31593 AAG31594 AAG31595 AAG31596 AAL35279 AAL35280 AAL35281 CAA34545 CAA39462 EAW66436 P12724 BC096060 AAH96060 BC096061 AAH96061 BC096062 AAH96062 BX280390 M28128 AAA50283 X15161 CAA33251 NM_002935 NP_002926
Function	Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. {ECO:0000269|PubMed:19450231, ECO:0000269|PubMed:2501794}.
Subcellular Location	Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
Top Pathways	Asthma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RNASE3 ELISA Kit (Sandwich ELISA) - LS-F4920 from LifeSpan Bioscience Category ELISA Kit Prices $690.00 Sizes 1 plate Sensitivity 78 pg/ml Range 78-5000 pg/ml

Human RNASE3 ELISA Kit (Sandwich ELISA) - LS-F11344 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 78-5000 pg/ml

ECP ELISA Kit - abx150337 from Abbexa Category ELISA Kit Sensitivity 0.124 ng/ml Range 0.313 ng/ml - 20 ng/ml

ECP ELISA Kit - abx150338 from Abbexa Category ELISA Kit Sensitivity 0.043 ng/ml Range 0.156 ng/ml - 10 ng/ml

Eosinophil cationic protein, RNASE3, Human, ELISA Kit - E1758h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.625-40 ng/mL

Ribonuclease A3 (RNASE3), Human, ELISA Kit - SEB758Hu from ARP American Research Products Category ELISA Kit Prices $685.00 Sizes 96 t Sensitivity 17pg/mL Range 39-2,500pg/mL

Ribonuclease A3/Eosinophil Cationic Protein, RNASE3/ECP, Human, ELISA Kit - E-EL-H1379 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 23.438 Range 39.063-2500pg/mL

Escherichia coli Protein (ECP), General, ELISA Kit - SEX655Ge from ARP American Research Products Category ELISA Kit Prices $768.00 Sizes 96 t Sensitivity 0.134ng/mL Range 0.312-20ng/mL

High Sensitive Escherichia coli Protein (ECP), ELISA Kit - hE71655Ge from ARP American Research Products Category ELISA Kit Prices $822.00 Sizes 96 t

High Sensitive Escherichia coli Protein (ECP), General, ELISA Kit - HEX655Ge from ARP American Research Products Category ELISA Kit Prices $842.00 Sizes 96 t Sensitivity 0.043ng/mL Range 0.156-10ng/mL

Human ECP ELISA Kit - HE0132 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine ECP ELISA Kit - AE0132 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Eosinophil cationic protein, ELISA Kit - MBS723200 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil cationic protein, ELISA Kit - MBS754454 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil Cationic Protein, ELISA Kit - MBS101398 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1ng/ml. Range 1.56ng/ml-50ng/ml.

Eosinophil Cationic Protein, ELISA Kit - MBS045859 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil cationic protein, ELISA Kit - MBS7249713 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil cationic protein, ELISA Kit - MBS741172 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,850.00, $5,340.00 Sizes 48 -strip-wells- (Competitive), 96 -strip-wells- (Competitive), 5x96-strip-wells- (Competitive), 10x96-strip-wells- (Competitive) Sensitivity 0.1 ng/mL

Eosinophil cationic protein, ELISA Kit - MBS737851 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/mL.

Eosinophil Cationic Protein - MBS023099 from MyBioSource Category ELISA Kit Prices $435.00, $600.00 Sizes 48 strip wells, 96 strip wells

Eosinophil Cationic Protein, ELISA Kit - MBS040508 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil cationic protein, ELISA Kit - MBS737882 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil cationic protein, ELISA Kit - MBS748892 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil cationic protein, ELISA Kit - MBS734306 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Eosinophil cationic protein, ELISA Kit - MBS753764 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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