RNASE3

Gene Symbol	RNASE3
Entrez Gene	6037
Alt Symbol	ECP, RNS3
Species	Human
Gene Type	protein-coding
Description	ribonuclease, RNase A family, 3
Other Description	RNase 3|cytotoxic ribonuclease|eosinophil cationic protein|ribonuclease 3
Swissprots	Q4VBC1 P12724 Q8WZ62 Q9GZN9 Q8WTP7
Accessions	AAG31589 AAG31590 AAG31591 AAG31592 AAG31593 AAG31594 AAG31595 AAG31596 AAL35279 AAL35280 AAL35281 CAA34545 CAA39462 EAW66436 P12724 BC096060 AAH96060 BC096061 AAH96061 BC096062 AAH96062 BX280390 M28128 AAA50283 X15161 CAA33251 NM_002935 NP_002926
Function	Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. {ECO:0000269|PubMed:19450231, ECO:0000269|PubMed:2501794}.
Subcellular Location	Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
Top Pathways	Asthma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Ribonuclease 3 full length protein - ab137138 from Abcam Category Protein Source E. coli Species Human

RNASE3 Antibody Blocking Peptide - LS-E2521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human RNASE3 Protein - NBP2-23415 from Novus Biologicals Category Protein Prices $299.00 Sizes 100 µg Source E.coli Species Human

RNASE3-Antibody-C-term-Blocking-peptide - BP13557b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human ECP protein - orb180400 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

ECP protein - orb169198 from Biorbyt Category Protein Prices $230.00, $442.00 Sizes 5 μg, 20 μg Source E. coli

RNASE3 protein (His tag) - 80R-2587 from Fitzgerald Category Protein Prices $270.00 Sizes 100 µg Source E.coli

Human Ribonuclease A3 Protein - abx068913 from Abbexa Category Protein Source E.coli Species Human

RNASE3 Blocking Peptide - abx063206 from Abbexa Category Peptide Species Human

RNASE3 (28-160, His-tag) - AR50633PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

RNASE3 (28-160, His-tag) - AR50633PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

RNASE3, 28-160 aa, Human, His tag, E.coli - 01-P1809 from ARP American Research Products Category Protein Prices $179.00, $369.00, $849.00 Sizes 20 µg, 100 µg, 500 µg Species Human

RNASE3 fusion protein - Ag17803 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RNASE3 Human - ENPS-675 from NeoScientific Category Protein Prices $65.00, $169.00, $3,510.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human RNASE3 Enzyme - BP001785-CA06 from Syd Labs Category Protein Prices $180.00, $528.00, $2,640.00 Sizes 10 µg, 50 µg, 1 mg Source HEK 293-derived. Species Human

Recombinant Human RNASE3, His-tagged - RNASE3-5319H from Creative Biomart Category Protein Source HEK293 Species Human

Recombinant Human RNASE3, GST-tagged - RNASE3-2323H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human ribonuclease, RNase A family, 3, His-tagged - RNASE3-370H from Creative Biomart Category Protein Source E.coli Species Human

Native Human Ribonuclease, RNase A Family, 3 - RNASE3-5318H from Creative Biomart Category Protein Source HumanEosinophils

Recombinant Ribonuclease A3 (RNASE3) - RPB758Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Ribonuclease A3 (RNASE3) - RPB758Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Ribonuclease A3 (RNASE3) - RPB758Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

RNASE3 Blocking Peptide - CBP2012 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

ECP (V151) Peptide - BS2876P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Ribonuclease A3 (RNASE3) - RPB758Hu01 from Cloud-clone Category Protein Source E.coli Species Human

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