RNASE3

Gene Symbol	RNASE3
Entrez Gene	6037
Alt Symbol	ECP, RNS3
Species	Human
Gene Type	protein-coding
Description	ribonuclease, RNase A family, 3
Other Description	RNase 3|cytotoxic ribonuclease|eosinophil cationic protein|ribonuclease 3
Swissprots	Q4VBC1 P12724 Q8WZ62 Q9GZN9 Q8WTP7
Accessions	AAG31589 AAG31590 AAG31591 AAG31592 AAG31593 AAG31594 AAG31595 AAG31596 AAL35279 AAL35280 AAL35281 CAA34545 CAA39462 EAW66436 P12724 BC096060 AAH96060 BC096061 AAH96061 BC096062 AAH96062 BX280390 M28128 AAA50283 X15161 CAA33251 NM_002935 NP_002926
Function	Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. Promotes E.coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content. {ECO:0000269|PubMed:19450231, ECO:0000269|PubMed:2501794}.
Subcellular Location	Secreted. Note=Located in the matrix of eosinophil large specific granule, which are released following activation by an immune stimulus.
Top Pathways	Asthma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

RNASE3 overexpression lysate - LY419004 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

RNASE3 293 Cell Lysate - 408888 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

RNASE3 Overexpression Lysate (Native) - NBP2-08055 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

RNASE3 Over-expression Lysate Product - GWB-78D835 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human RNASE3 Knockdown Stable Cell Line - CSC-DC013348 from Creative biogene Category Cell Line Species Human

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