SERPIND1

Gene Symbol SERPIND1
Entrez Gene 3053
Alt Symbol D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Other Description heparin cofactor 2|leuserpin 2|protease inhibitor leuserpin-2|serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1|serpin D1
Swissprots D3DX34 P05546 B2RAI1 Q6IBZ5
Accessions AAA36185 AAA52641 EAX02941 EAX02942 P05546 AK225292 AK314200 BAG36878 BC035028 AAH35028 BP237845 CR456573 CAG30459 CU013172 CAK54603 CU013460 CAK54902 DQ891203 ABM82129 DQ894386 ABM85312 M12849 AAA52642 X03498 CAA27218 NM_000185 NP_000176
Function Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. {ECO:0000269|PubMed:1939083}.
Tissue Specificity Expressed predominantly in liver. Also present in plasma.
Top Pathways Complement and coagulation cascades

SERPIND1-Over-expression-Lysate - LY11557a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag SERPIND1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the SERPIND1 gene

SERPIND1 293T Cell Transient Overexpression Lysate(Denatured) - H00003053-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SERPIND1 293 Cell Lysate - 410309 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

Serpin D1/Heparin Cofactor II Overexpression Lysate (Denatured) - H00003053-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
Lane 1: SERPIND1 transfected lysate (55 KDa) Lane 2: Non-transfected lysate.

HCII (h4): 293T Lysate - sc-170579 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

HCII (h5): 293 Lysate - sc-158588 from Santa Cruz Biotechnology

Category Cell Lysate
Prices $205.00
Sizes 100 µg/200 µl
Species Human

SERPIND1 Over-expression Lysate Product - GWB-5B571B from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Human SerpinD1 HEK293 Cell Lysate (WB positive control) - 10295-H08HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human SerpinD1 Human Cells Transfected Lysate (positive control) (denatured) - orb173003 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Human

Serpin D1/Heparin Cofactor II Overexpression Lysate (Native) - NBP2-11151 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Heparin Cofactor II Overexpression Lysate (Adult Normal) [NBP2-11151] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Heparin Cofactor II.

Panoply™ Human SERPIND1 Knockdown Stable Cell Line - CSC-DC014057 from Creative biogene

Category Cell Line
Species Human
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