SERPIND1

Gene Symbol	SERPIND1
Entrez Gene	3053
Alt Symbol	D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10
Species	Human
Gene Type	protein-coding
Description	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Other Description	heparin cofactor 2|leuserpin 2|protease inhibitor leuserpin-2|serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1|serpin D1
Swissprots	D3DX34 P05546 B2RAI1 Q6IBZ5
Accessions	AAA36185 AAA52641 EAX02941 EAX02942 P05546 AK225292 AK314200 BAG36878 BC035028 AAH35028 BP237845 CR456573 CAG30459 CU013172 CAK54603 CU013460 CAK54902 DQ891203 ABM82129 DQ894386 ABM85312 M12849 AAA52642 X03498 CAA27218 NM_000185 NP_000176
Function	Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. {ECO:0000269|PubMed:1939083}.
Tissue Specificity	Expressed predominantly in liver. Also present in plasma.
Top Pathways	Complement and coagulation cascades

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Heparin Cofactor II full length protein - ab191977 from Abcam Category Protein Prices $597.00 Sizes 50 µg Source HEK 293 cells Species Human

Active human Heparin Cofactor II full length protein - ab185271 from Abcam Category Protein Prices $1,646.00 Sizes 50 µg Source Native Species Human

Human Heparin Cofactor II full length protein - ab158647 from Abcam Category Protein Source Wheat germ Species Human

Human Heparin Cofactor II full length protein - ab62249 from Abcam Category Protein Source Native Species Human

Human Heparin Cofactor II protein fragment - ab183173 from Abcam Category Protein Source E. coli Species Human

SERPIND1 / Heparin Cofactor 2 Antibody Blocking Peptide - LS-E15220 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Serpin D1/Heparin Cofactor II Recombinant Protein - H00003053-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Serpin D1/Heparin Cofactor II, CF - 3198-PI-010 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (stably transfected)-derived, Gly20-Ser499, with a C-terminal 10-His tag

Human SerpinD1 His tag protein - orb83117 from Biorbyt Category Protein Prices $323.00, $527.00 Sizes 10 μg, 20 μg Source Human Species Human

Mouse SerpinD1 His tag protein - orb83480 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 10 μg, 20 μg Source Mouse Species Human

SERPIND1 Blocking Peptide - 33R-9813 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SERPIND1 protein (His tag) - 80R-3898 from Fitzgerald Category Protein Prices $275.00 Sizes 100 µg Source E.coli

Human Heparin Cofactor II Protein - abx067065 from Abbexa Category Protein Source E.coli Species Human

SERPIND1 (58-499, His-tag) - AR51585PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 500 µg Source E. coli Species Human

SERPIND1 (58-499, His-tag) - AR51585PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 100 µg Source E. coli Species Human

SERPIND1 - H00003053-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SERPIND1 - H00003053-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SERPIND1 Recombinant Protein - 96-381 from ProSci Category Protein Prices $425.00 Sizes 50 µg Source HEK293 cells Species Human

SERPIND1 fusion protein - Ag3637 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, T-HIS Species Human

Recombinant Human SERPIND1, His-tagged - SERPIND1-3157H from Creative Biomart Category Protein Source Human Cells.

Recombinant Human SERPIND1, His-tagged - SERPIND1-2599H from Creative Biomart Category Protein Source E.coli Species Human

Native Human Heparin Cofactor II - SERPIND1-12H from Creative Biomart Category Protein Source Human plasma Species Human

Recombinant Heparin Cofactor II (HCII) - RPA284Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Heparin Cofactor II (HCII) - RPA284Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Heparin Cofactor II (HCII) - RPA284Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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