SERPIND1

Gene Symbol SERPIND1
Entrez Gene 3053
Alt Symbol D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Other Description heparin cofactor 2|leuserpin 2|protease inhibitor leuserpin-2|serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1|serpin D1
Swissprots D3DX34 P05546 B2RAI1 Q6IBZ5
Accessions AAA36185 AAA52641 EAX02941 EAX02942 P05546 AK225292 AK314200 BAG36878 BC035028 AAH35028 BP237845 CR456573 CAG30459 CU013172 CAK54603 CU013460 CAK54902 DQ891203 ABM82129 DQ894386 ABM85312 M12849 AAA52642 X03498 CAA27218 NM_000185 NP_000176
Function Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. {ECO:0000269|PubMed:1939083}.
Tissue Specificity Expressed predominantly in liver. Also present in plasma.
Top Pathways Complement and coagulation cascades

HCII CRISPR/Cas9 KO Plasmid (h) - sc-409626 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII HDR Plasmid (h) - sc-409626-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII Double Nickase Plasmid (h) - sc-409626-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII Double Nickase Plasmid (h2) - sc-409626-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII CRISPR Activation Plasmid (h) - sc-409626-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII CRISPR Activation Plasmid (h2) - sc-409626-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII Lentiviral Activation Particles (h) - sc-409626-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII Lentiviral Activation Particles (h2) - sc-409626-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HCII siRNA (h) - sc-72117 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HCII shRNA Plasmid (h) - sc-72117-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HCII shRNA (h) Lentiviral Particles - sc-72117-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU150111 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1643 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1643 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR06099 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr06099

SERPIND1 siRNA (Human) - CRH2078 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SERPIND1 - MBS8223501 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SERPIND1 (NM_000185.3) - SHH405336 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SERPIND1(NM_000185.3) - SHR218290 from Creative biogene

Category siRNA
Species Reactivities Human

SERPIND1 shRNA Plasmid (Human) - CHH2078 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SERPIND1 miRNA 3'UTR clone - MiUTR1H-09304 from Creative biogene

Species Reactivities Human
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