SERPIND1

Gene Symbol SERPIND1
Entrez Gene 3053
Alt Symbol D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10
Species Human
Gene Type protein-coding
Description serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Other Description heparin cofactor 2|leuserpin 2|protease inhibitor leuserpin-2|serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1|serpin D1
Swissprots D3DX34 P05546 B2RAI1 Q6IBZ5
Accessions AAA36185 AAA52641 EAX02941 EAX02942 P05546 AK225292 AK314200 BAG36878 BC035028 AAH35028 BP237845 CR456573 CAG30459 CU013172 CAK54603 CU013460 CAK54902 DQ891203 ABM82129 DQ894386 ABM85312 M12849 AAA52642 X03498 CAA27218 NM_000185 NP_000176
Function Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). Also inhibits chymotrypsin, but in a glycosaminoglycan-independent manner. {ECO:0000269|PubMed:1939083}.
Tissue Specificity Expressed predominantly in liver. Also present in plasma.
Top Pathways Complement and coagulation cascades

HCII (N-18) - sc-25250 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
HCII (N-18): sc-25250. Western blot analysis of HCII expression in CCRF-CEM whole cell lysate.

HCII (H-300) - sc-366443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

HCII (74E5) - sc-69784 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
HCII (74E5): sc-69784. Western blot analysis of HCII expression in non-transfected: sc-117752 (A) and human HCII transfected: sc-170579 (B) 293T whole cell lysates.

Anti-Heparin Cofactor II antibody - ab196758 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human liver carcinoma tissue labeling Heparin Cofactor II with ab196758 at 1/50 dilution (left) and synthesized peptide (right).

Anti-Heparin Cofactor II antibody - ab153929 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Heparin Cofactor II antibody (ab153929) at 1/10000 dilution + HepG2 cell lysate at 30 µg

Anti-Heparin Cofactor II antibody - ab61371 from Abcam

Prices $370.00
Sizes 1 mg
Host Sheep
Clonality Polyclonal

Anti-Heparin Cofactor II antibody - ab97846 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-Heparin Cofactor II antibody (ab97846) at 1 µg/ml (in 5% skim milk / PBS buffer) + THP1 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Heparin Cofactor II antibody - ab31661 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Heparin Cofactor II antibody [74E5] - ab51051 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 74E5
All lanes : Anti-Heparin Cofactor II antibody [74E5] (ab51051) at 1/2000 dilutionLane 1 : Heparin Cofactor II isolated from human plasmaLane 2 : Human plasma

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C24193 from LifeSpan Bioscience

Prices $275.00
Sizes 1 mg
Host Goat
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C24192 from LifeSpan Bioscience

Prices $265.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C24194 from LifeSpan Bioscience

Prices $495.00
Sizes 500 µg
Host Goat
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody (aa20-499, Biotin) - LS-C39047 from LifeSpan Bioscience

Prices $650.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C129656 from LifeSpan Bioscience

Prices $315.00
Sizes 1 mg
Host Sheep
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C150904 from LifeSpan Bioscience

Prices $305.00
Sizes 1 mg
Host Sheep
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C147784 from LifeSpan Bioscience

Prices $380.00
Sizes 1 ml
Host Rabbit
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody (Asp68) - LS-C193125 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C193656 from LifeSpan Bioscience

Prices $355.00
Sizes 5 mg
Host Goat
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody (HRP) - LS-C193823 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C193898 from LifeSpan Bioscience

Prices $515.00
Sizes 500 µg
Host Goat
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody (aa276-499, Biotin) - LS-C298013 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody (aa276-499, FITC) - LS-C305110 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody - LS-C62004 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-SERPIND1 / Heparin Cofactor 2 Antibody (aa41-90) - LS-C118757 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human liver carcinoma tissue, using Heparin Cofactor II Antibody. The picture on the right is treated with the synthesized peptide.

Anti-SERPIND1 / Heparin Cofactor 2 Antibody (aa323-372) - LS-C107501 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SERPIND1 / Heparin Cofactor II antibody LS-C107501 Western blot of THP-1 cell lysate.
Search more