GOPC

Gene Symbol	GOPC
Entrez Gene	57120
Alt Symbol	CAL, FIG, GOPC1, PIST, dJ94G16.2
Species	Human
Gene Type	protein-coding
Description	golgi-associated PDZ and coiled-coil motif containing
Other Description	CFTR-associated ligand|Golgi associated PDZ and coiled-coil motif containing protein|Golgi-associated PDZ and coiled-coil motif-containing protein|PDZ protein interacting specifically with TC10|PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10|dJ94G16.2 PIST|fused in glioblastoma|golgi-associated PDZ and coiled-coil motif containing protein
Swissprots	Q9HD26 Q969U8 Q59FS4 A6NM30
Accessions	EAW48204 EAW48205 Q9HD26 AB209385 BAD92622 AF287894 AAG00572 AF450008 AAL47160 AJ420540 AK025074 AK314486 AY033606 AAK57733 BC009553 AAH09553 BX419592 DA109449 HQ447312 ADQ31799 KF420122 AGU13713 KF420123 AGU13714 NM_001017408 NP_001017408 NM_020399 NP_065132
Function	Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes. {ECO:0000269|PubMed:11707463, ECO:0000269|PubMed:14570915, ECO:0000269|PubMed:15358775}.
Subcellular Location	Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Enriched in synaptosomal and postsynaptic densities (PSD) fractions. Expressed in cell bodies and dendrites of Purkinje cells. Localized at the trans-Golgi network (TGN) of spermatids and the medulla of round spermatides. {ECO:0000250}.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:11162552, ECO:0000269|PubMed:11384996, ECO:0000269|PubMed:11707463}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-GOPC-cDNA-Clone - DC02689 from Abgent, a WuXi AppTec company Prices $612.90 Sizes 10 µg Species Human Accession BC009553

GOPC - MBS1278388 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC009553

Human GOPC ORF Clone(NM_001017408.2) - CDCR341797 from Creative Biomart Species Human Accession NM_001017408.2

Human GOPC ORF Clone(NM_001017408.2) - CDCR341798 from Creative Biomart Species Human Accession NM_001017408.2

Human GOPC ORF Clone(NM_001017408.2) - CDCL165021 from Creative Biomart Species Human Accession NM_001017408.2

Human GOPC Gene cDNA clone plasmid - HG14911-G from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG14911-ACG from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG14911-ANG from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, C-Flag tag - HG14911-CF from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid - HG14911-UT from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, N-Myc tag - HG14911-NM from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, N-HA tag - HG14911-NY from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, C-Myc tag - HG14911-CM from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, N-His tag - HG14911-NH from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, C-His tag - HG14911-CH from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, C-HA tag - HG14911-CY from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG14911-ACR from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG14911-ANR from Sino Biological Species Human

Human GOPC / PIST Gene ORF cDNA clone expression plasmid, N-Flag tag - HG14911-NF from Sino Biological Species Human

Human GOPC ORF Clone(NM_001017408.2) - CDCR341797 from Creative biogene Species Human

Human GOPC ORF Clone (BC009553) - CDCS406589 from Creative biogene Species Human Accession Q9HD26

Human GOPC ORF clone (BC009553) - CDCB158662 from Creative biogene Species Human

Search more