GOPC

Gene Symbol	GOPC
Entrez Gene	57120
Alt Symbol	CAL, FIG, GOPC1, PIST, dJ94G16.2
Species	Human
Gene Type	protein-coding
Description	golgi-associated PDZ and coiled-coil motif containing
Other Description	CFTR-associated ligand|Golgi associated PDZ and coiled-coil motif containing protein|Golgi-associated PDZ and coiled-coil motif-containing protein|PDZ protein interacting specifically with TC10|PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10|dJ94G16.2 PIST|fused in glioblastoma|golgi-associated PDZ and coiled-coil motif containing protein
Swissprots	Q9HD26 Q969U8 Q59FS4 A6NM30
Accessions	EAW48204 EAW48205 Q9HD26 AB209385 BAD92622 AF287894 AAG00572 AF450008 AAL47160 AJ420540 AK025074 AK314486 AY033606 AAK57733 BC009553 AAH09553 BX419592 DA109449 HQ447312 ADQ31799 KF420122 AGU13713 KF420123 AGU13714 NM_001017408 NP_001017408 NM_020399 NP_065132
Function	Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes. {ECO:0000269|PubMed:11707463, ECO:0000269|PubMed:14570915, ECO:0000269|PubMed:15358775}.
Subcellular Location	Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Enriched in synaptosomal and postsynaptic densities (PSD) fractions. Expressed in cell bodies and dendrites of Purkinje cells. Localized at the trans-Golgi network (TGN) of spermatids and the medulla of round spermatides. {ECO:0000250}.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:11162552, ECO:0000269|PubMed:11384996, ECO:0000269|PubMed:11707463}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PIST peptide - ab39848 from Abcam Category Peptide Species Human

Human PIST peptide - ab23145 from Abcam Category Peptide Species Human

Human PIST protein fragment - ab93743 from Abcam Category Protein Source E. coli Species Human

GOPC / PIST Antibody Blocking Peptide - LS-E2449 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GOPC / PIST Antibody Blocking Peptide - LS-E25667 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GOPC / PIST Antibody Blocking Peptide - LS-E30186 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GOPC / PIST Antibody Blocking Peptide - LS-E30185 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

GOPC / PIST Antibody Blocking Peptide - LS-E8811 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GOPC / PIST Antibody Blocking Peptide - LS-E8812 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PIST Protein - NBP1-40404 from Novus Biologicals Category Protein Prices $269.00 Sizes 100 µg Source E. coli Species Human

PIST Blocking Peptide - NBP1-77243PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PIST Blocking Peptide - NBP1-77242PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

PIST Recombinant Protein - P4315 from Novus Biologicals Category Protein Prices $669.00 Sizes 100 µg Species Human

PIST Recombinant Protein - P3403 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Human

GOPC-Antibody-C-term-Blocking-peptide - BP13470b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PIST-Antibody-Center-Blocking-Peptide - BP7262c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PIST-Antibody-C-term-Blocking-Peptide - BP7262b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PIST blocking peptide - GTX26040-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Dog, Bovine

GOPC Protein (OPPA01878) - OPPA01878 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human GOPC protein (His Tag) - orb138938 from Biorbyt Category Protein Prices $357.00, $748.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Human Golgi-Associated PDZ and Coiled-Coil Motif Containing protein - orb81146 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 25 μg Source E.coli

GOPC Blocking Peptide - 33R-8073 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GOPC Blocking Peptide - 33R-2799 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GOPC protein (His tag) - 80R-1261 from Fitzgerald Category Protein Prices $220.00 Sizes 100 µg Source E.coli

PIST Peptide - AC21-0497-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

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