SLC22A4

Gene Symbol SLC22A4
Entrez Gene 6583
Alt Symbol OCTN1
Species Human
Gene Type protein-coding
Description solute carrier family 22 (organic cation/zwitterion transporter), member 4
Other Description ET transporter|ergothioneine transporter|integral membrane transport protein|organic cation/carnitine transporter 1|solute carrier family 22 (organic cation/ergothioneine transporter), member 4|solute carrier family 22 member 4
Swissprots Q9H015 O14546
Accessions BAJ13468 CAJ56219 EAW62340 Q9H015 AB007448 BAA23356 AK309243 AK310818 BC028313 AAH28313 DQ890816 ABM81742 DQ893972 ABM84898 Y09881 CAA71007 XM_006714675 XP_006714738 XM_011543589 XP_011541891 XR_948289 NM_003059 NP_003050
Function Sodium-ion dependent, low affinity carnitine transporter. Probably transports one sodium ion with one molecule of carnitine. Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. Relative uptake activity ratio of carnitine to TEA is 1.78. A key substrate of this transporter seems to be ergothioneine (ET). {ECO:0000269|PubMed:10215651, ECO:0000269|PubMed:15795384}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity Widely expressed. Highly expressed in whole blood, bone marrow, trachea and fetal liver. Weakly expressed in kidney, skeletal muscle, prostate, lung, pancreas, placenta, heart, uterus, spleen and spinal cord. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. Predominantly expressed in CD14 cells in peripheral blood mononuclear cells. {ECO:0000269|PubMed:14608356, ECO:0000269|PubMed:15107849, ECO:0000269|PubMed:9426230}.
Top Pathways Choline metabolism in cancer

solute carrier family 22 (organic cation/ergothioneine transporter) , member 4, ELISA Kit - MBS9325506 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Organic Cation/Ergothioneine Transporter (OCTN1), ELISA Kit - MBS2024893 from MyBioSource

Category ELISA Kit
Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00
Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity Typically less than 30pg/mL.
Range 78.13-5000pg/mL

ELISA Kit for Organic Cation/Ergothioneine Transporter (OCTN1) - SEE444Hu from Uscn Life Science Inc.

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 30pg/mL.
Range 78.13-5000pg/mL The standard curve concentrations used for the ELISA’s were 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312.5pg/mL, 156.25pg/mL, 78.13pg/mL

ELISA Kit for Organic Cation/Ergothioneine Transporter (OCTN1) - SEE444Hu from Cloud-clone

Category ELISA Kit
Sensitivity The minimum detectable dose of this kit is typically less than 30pg/mL.
Range 78.125-5000pg/mL The standard curve concentrations used for the ELISA's were 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312.5pg/mL, 156.25pg/mL, 78.125pg/mL

Human Organic Cation/Ergothioneine Transporter (OCTN1) ELISA Kit - EKU08465 from Biomatik

Category ELISA Kit
Prices $735.00, $3,234.00, $5,880.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 27 pg/mL
Range 78.12-5000 pg/mL

Human Organic Cation/Ergothioneine Transporter ELISA Kit - abx156831 from Abbexa

Category ELISA Kit
Range 78.13 pg/ml - 5000 pg/ml

Human SLC22A4 / OCTN1 ELISA Kit (Sandwich ELISA) - LS-F25459 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 27 pg/ml
Range 78.13-5000 pg/ml

Human SLC22A4 ELISA Kit - E035927 from Biobool

Category ELISA Kit

SLC22A4 ELISA Kit (Human) (OKCD01211) - OKCD01211 from Aviva Systems Biology

Category ELISA Kit
Prices $545.00
Sizes 96 wells
Sensitivity < 27 pg/mL
Range 78.12-5,000 pg/mL

Human Solute carrier family 22 member 4 (SLC22A4) ELISA Kit - AE19027HU from ARP American Research Products

Category ELISA Kit
Prices $549.00
Sizes 96 t
Sensitivity 27 pg/mL
Range 78.12-5000 pg/mL

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9353280 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9357247 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9358139 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9354501 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9360407 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9368201 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9351553 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9356909 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9368875 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9361543 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9357510 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9350108 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9365504 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9360167 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Solute Carrier Family 22 Member 4 (SLC22A4), ELISA Kit - MBS9367590 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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