BLOC1S6

Gene Symbol BLOC1S6
Entrez Gene 26258
Alt Symbol BLOS6, HPS9, PA, PALLID, PLDN
Species Human
Gene Type protein-coding
Description biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
Other Description BLOC-1 subunit 6|biogenesis of lysosomal organelles complex-1, subunit 5, pallidin|biogenesis of lysosome-related organelles complex 1 subunit 6|pallid protein homolog|syntaxin 13 binding protein 1|syntaxin 13-interacting protein pallid
Swissprots Q9UL45
Accessions EAW77330 Q9UL45 AF080470 AAF08343 AF131859 AK057545 AK128626 BAG54702 AK315581 BAG37954 BC004819 AAH04819 BC026289 JF432566 ADZ15783 NM_012388 NP_036520
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. {ECO:0000269|PubMed:17182842, ECO:0000269|PubMed:21998198}.
Subcellular Location Cytoplasm. Endomembrane system; Peripheral membrane protein. Note=It can exist as a soluble protein as well as a peripheral membrane protein.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:12019270, ECO:0000269|PubMed:12191018}.

Pallidin (S-15) - sc-33458 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Pallidin (S-15): sc-33458. Western blot analysis of Pallidin expression in mouse spleen (A) and mouse brain (B) tissue extracts.

Anti-Pallidin antibody - ab129010 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Pallidin antibody (ab129010) at 1/1000 dilutionLane 1 : A431 cell lysateLane 2 : HeLa cell lysateLane 3 : K562 cell lysateLane 4 : MCF7 cell lysateLane 5 : Human fetal kidney lysate

Anti-Pallidin antibody - ab10145 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PLDN / Pallidin Antibody (clone 1E2) - LS-C337599 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E2
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PLDN mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-PLDN / Pallidin Antibody (aa1-172) - LS-C178990 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PLDN / Pallidin Antibody (clone 1H9) - LS-C173735 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H9
IHC of paraffin-embedded Human tonsil using anti-PLDN mouse monoclonal antibody.

Anti-PLDN / Pallidin Antibody (aa159-172) - LS-C55228 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (1 ug/ml) of A431 lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-PLDN / Pallidin Antibody (N-Terminus) - LS-C107803 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PLDN antibody LS-C107803 Western blot of PANC1 cell lysate.

Anti-PLDN / Pallidin Antibody (aa36-85) - LS-C102572 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PLDN antibody LS-C102572 Western blot of Jurkat lysate.

Pallidin Antibody (1H9) - NBP2-01763 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1H9
Western Blot: Pallidin Antibody (1H9) [NBP2-01763] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY Pallidin (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-Pallidin.

Pallidin Antibody - NBP1-87357 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Pallidin Antibody [NBP1-87357] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

Pallidin Antibody - NB100-1234 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: Pallidin Antibody [NB100-1234] - HEK293 overexpressing PLDN and probed with (mock transfection in first lane).

Pallidin Antibody (2H8) - H00026258-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H8
Western Blot: Pallidin Antibody (2H8) [H00026258-M01] - Analysis of PLDN expression in transfected 293T cell line by PLDN monoclonal antibody (M01), clone 2H8.Lane 1: PLDN transfected lysate(19.7 KDa).Lane 2: Non-transfected lysate.

Pallidin Antibody (3D2) - H00026258-M10 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D2

Pallidin Antibody - H00026258-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Pallidin Antibody [H00026258-B01P] - Analysis of PLDN expression in human spleen.

Anti-BLOC1S6 antibody produced in rabbit - HPA039928 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PLDN: <B>Cat. No. HPA039928</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells.

Monoclonal Anti-PLDN, (N-terminal) antibody produced in mouse - SAB1402562 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2H8
<B>Immunoblotting</B><BR/>Monoclonal Anti-PLDN, antibody produced in mouse, clone 2H8, purified immunoglobulin: <B>Cat. No. SAB1402562</B>: Antibody concentration: 1 μg/mL. Specific band of ~37 kDa using immunogen protein lysate.

Anti-PLDN antibody produced in mouse - SAB1400488 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-PLDN, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400488</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~19.7 kDa using human spleen lysate.

Anti-PLDN antibody produced in rabbit - SAB2101826 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLDN: <B>Cat. No.SAB2101826</B>: PLDN in Jurkat cell lysate with PLDN antibody at 1.0 μg/mL.

Anti-Pallidin antibody produced in goat - SAB2500742 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-Pallidin: <B>Cat. No. SAB2500742</B>: staining (1 μg/mL) of A431 lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-PLDN, (N-terminal) antibody produced in rabbit - SAB2105000 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PLDN, antibody produced in rabbit: <B>Cat. No. SAB2105000</B>: Immunoblotting analysis of PLDN in PANC1 cell lysate with PLDN anitbody at 1 μg/mL.

Monoclonal Anti-PLDN antibody produced in mouse - SAB1405011 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D2
<B>Immunoblotting</B><BR/>Monoclonal Anti-PLDN: <B>Cat. No. SAB1405011</B>: Antibody concentration: 1 μg/mL. Specific band of ~45 kDa using immunogen protein lysate.

PLDN antibody - N-terminal region (ARP54889_P050) - ARP54889_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PLDN antibody - middle region (ARP54890_P050) - ARP54890_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Pallidin-Antibody - AF1779a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1779a staining (1 µg/ml) of A431 lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
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