BLOC1S6

Gene Symbol BLOC1S6
Entrez Gene 26258
Alt Symbol BLOS6, HPS9, PA, PALLID, PLDN
Species Human
Gene Type protein-coding
Description biogenesis of lysosomal organelles complex-1, subunit 6, pallidin
Other Description BLOC-1 subunit 6|biogenesis of lysosomal organelles complex-1, subunit 5, pallidin|biogenesis of lysosome-related organelles complex 1 subunit 6|pallid protein homolog|syntaxin 13 binding protein 1|syntaxin 13-interacting protein pallid
Swissprots Q9UL45
Accessions EAW77330 Q9UL45 AF080470 AAF08343 AF131859 AK057545 AK128626 BAG54702 AK315581 BAG37954 BC004819 AAH04819 BC026289 JF432566 ADZ15783 NM_012388 NP_036520
Function Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. {ECO:0000269|PubMed:17182842, ECO:0000269|PubMed:21998198}.
Subcellular Location Cytoplasm. Endomembrane system; Peripheral membrane protein. Note=It can exist as a soluble protein as well as a peripheral membrane protein.
Tissue Specificity Widely expressed. {ECO:0000269|PubMed:12019270, ECO:0000269|PubMed:12191018}.

Pallidin CRISPR/Cas9 KO Plasmid (h) - sc-411906 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin HDR Plasmid (h) - sc-411906-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin Double Nickase Plasmid (h) - sc-411906-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin Double Nickase Plasmid (h2) - sc-411906-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin CRISPR Activation Plasmid (h) - sc-411906-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin CRISPR Activation Plasmid (h2) - sc-411906-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin Lentiviral Activation Particles (h) - sc-411906-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin Lentiviral Activation Particles (h2) - sc-411906-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Pallidin siRNA (h) - sc-45204 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pallidin shRNA Plasmid (h) - sc-45204-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Pallidin shRNA (h) Lentiviral Particles - sc-45204-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU037831 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN16942 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16942 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR13894 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr13894

BLOC1S6 siRNA (Human) - CRH8783 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BLOC1S6 - MBS8224387 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PLDN (NM_012388.2) - SHH377404 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human PLDN(NM_012388.2) - SHR121566 from Creative biogene

Category siRNA
Species Reactivities Human

Human BLOC1S6 siRNA - orb269285 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BLOC1S6 shRNA Plasmid (Human) - CHH8783 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BLOC1S6 miRNA 3'UTR clone - MiUTR1H-07988 from Creative biogene

Species Reactivities Human
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