SKP1

Gene Symbol	SKP1
Entrez Gene	6500
Alt Symbol	EMC19, OCP-II, OCP2, SKP1A, TCEB1L, p19A
Species	Human
Gene Type	protein-coding
Description	S-phase kinase-associated protein 1
Other Description	OCP-2|RNA polymerase II elongation factor-like protein OCP2|SIII|cyclin A/CDK2-associated p19|cyclin A/CDK2-associated protein p19|cyclin-A/CDK2-associated protein p19|organ of Corti protein 2|organ of Corti protein II|p19skp1|transcription elongation factor B polypeptide 1-like
Swissprots	D3DQ98 P63208 D3DQ97
Accessions	AAB50032 AAB50264 AAB50265 EAW62270 EAW62271 EAW62272 EAW62273 EAW62274 EAW62275 EAW62276 P63208 AI025746 AI028694 AK057110 BC009839 AAH09839 BC020798 AAH20798 BC025673 AAH25673 BC065730 AAH65730 BI552966 BI670085 BQ632052 DQ891512 ABM82438 DQ894703 ABM85629 EU831628 ACE87228 EU831713 ACE86547 U33760 AAC50241 U37558 AAA79202 Z47087 CAA87392 NM_006930 NP_008861 NM_170679 NP_733779
Function	Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA. SCF(BTRC) directs ubiquitination of NFKBIB, NFKBIE, ATF4, SMAD3, SMAD4, CDC25A, FBXO5 and probably NFKB2. SCF(SKP2) directs ubiquitination of phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. SCF(SKP2) directs ubiquitination of ORC1, CDT1, RBL2, ELF4, CDKN1A, RAG2, FOXO1A, and probably MYC and TAL1. SCF(FBXW7) directs ubiquitination of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. SCF(F
Top Pathways	Wnt signaling pathway, Cell cycle, Ubiquitin mediated proteolysis, TGF-beta signaling pathway, Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat SKP1 ELISA Kit (Cell-Based ELISA) - LS-F2309 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Human SKP1 ELISA Kit (Sandwich ELISA) - LS-F9694 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Elongin A, EloA, Human, ELISA Kit - CSB-E09196h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

S-Phase Kinase Associated Protein 1 (SKP1), Human, ELISA Kit - SEF883Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.054ng/mL Range 0.156-10ng/mL

S-phase kinase-associated protein 1 (SKP1), Human, ELISA Kit - CSB-EL021360HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

S-phase kinase-associated protein 1 (SKP1), Human, ELISA Kit - E01S0366 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

S phase kinase associated protein 1 (SKP1), ELISA Kit - MBS7246542 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

SKP1A/p19 Colorimetric Cell-Based ELISA Kit - CB5634 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

S-phase kinase-associated protein 1, ELISA Kit - MBS919742 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 7.81 pg/ml Range 31.25 pg/ml-2000 pg/ml

ELISA Kit for S-Phase Kinase Associated Protein 1 (SKP1) - SEF883Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human S-phase kinase-associated protein 1(SKP1) ELISA kit - CSB-EL021360HU from Cusabio Category ELISA Kit Sensitivity 7.81pg/ml Range 31.25 pg/ml-2000 pg/ml

ELISA Kit for S-Phase Kinase Associated Protein 1 (SKP1) - SEF883Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.054ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human SKP1 ELISA Kit - abx153099 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

SKP1A/p19 ELISA Kit - DEIA-XYA1622 from Creative Diagnostics Category ELISA Kit

Human SKP1 ELISA Kit - abx571919 from Abbexa Category ELISA Kit Sensitivity 0.054 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human SKP1 ELISA Kit - E034061 from Biobool Category ELISA Kit Sensitivity 7.81 pg/ml

SKP1 ELISA Kit (Human) (OKCD00480) - OKCD00480 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.054 ng/mL Range 0.156-10 ng/mL

Human S-phase kinase-associated protein 1 (SKP1) ELISA Kit - AE19429HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.054 ng/mL Range 0.156-10 ng/mL

S-Phase Kinase Associated Protein 1 (SKP1), ELISA Kit - MBS456153 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.054ng/mL Range 0.156-10ng/mL

SKP1A/p19 Colorimetric Cell-Based ELISA Kit - EKA50545 from Biomatik Category ELISA Kit Prices $399.00 Sizes 96 tests Sensitivity At least 5000 cells/well Range Qualitative

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