CHRDL1

Gene Symbol	CHRDL1
Entrez Gene	91851
Alt Symbol	CHL, MGC1, MGCN, NRLN1, VOPT, dA141H5.1
Species	Human
Gene Type	protein-coding
Description	chordin-like 1
Other Description	chordin-like protein 1|neuralin 1|neuralin-1|neurogenesin-1|ventroptin
Swissprots	Q539E4 B1AKD0 Q9Y3H7 Q9BU40 E9PGS5 D3DUY6 B4DMP3
Accessions	EAX02655 EAX02656 EAX02657 Q9BU40 AA057564 AB209548 BAD92785 AK092245 BAG52508 AK293106 BAF85795 AK297563 BAG59955 AK312270 AY608914 AAU25841 BC002909 AAH02909 BP377491 DC404314 XM_005262221 XP_005262278 XM_005262222 XP_005262279 XM_005262223 XP_005262280 XM_005262224 XP_005262281 NM_001143981 NP_001137453 NM_001143982 NP_001137454 NM_001143983 NP_001137455 NM_145234 NP_660277
Function	Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development. {ECO:0000250, ECO:0000269|PubMed:18587495, ECO:0000269|PubMed:22284829}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Expressed in the developing cornea and in the eye anterior segment in addition to the retina. Differentially expressed in the fetal brain. There is high expression in cerebellum and neocortex. Expressed in retinal pericytes. {ECO:0000269|PubMed:18587495, ECO:0000269|PubMed:22284829}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CHRDL1 cDNA clone(NM_001143982.1) - CDFH003633 from Creative Biomart Species Human Accession NM_001143982.1

Human CHRDL1 cDNA clone(NM_001143981.1) - CDFH003634 from Creative Biomart Species Human Accession NM_001143981.1

Human CHRDL1 ORF Clone(NM_001143981.1) - CDCL158798 from Creative Biomart Species Human Accession NM_001143981.1

Human CHRDL1 ORF Clone(NM_001143981.1) - CDCL158799 from Creative Biomart Species Human Accession NM_001143981.1

Human CHRDL1 ORF Clone(NM_001143981.1) - CDCR352009 from Creative Biomart Species Human Accession NM_001143981.1

Human CHRDL1 ORF Clone(NM_001143982.1) - CDCR352010 from Creative Biomart Species Human Accession NM_001143982.1

Human CHRDL1 ORF Clone(NM_001143982.1) - CDCR352011 from Creative Biomart Species Human Accession NM_001143982.1

Human CHRDL1 ORF Clone(NM_001143981.1) - CDCR352016 from Creative Biomart Species Human Accession NM_001143981.1

Human CHRDL1 ORF clone(NM_001143981.1) - CDCL183561 from Creative Biomart Species Human Accession NM_001143981.1

Human ARSB Gene ORF cDNA clone in cloning vector - HG13674-G from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, C-His tag - HG13674-CH from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13674-ACG from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, N-HA tag - HG13674-NY from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13674-ACR from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13674-NF from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13674-NM from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13674-CF from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, N-His tag - HG13674-NH from Sino Biological Species Human

Human ARSB Gene ORF cDNA clone expression plasmid, C-HA tag - HG13674-CY from Sino Biological Species Human

Human Chordin-Like 1/CHRDL1 Gene ORF cDNA clone in cloning vector - HG10866-M from Sino Biological Species Human

Human Chordin-Like 1/CHRDL1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG10866-CM from Sino Biological Species Human

Human Chordin-Like 1/CHRDL1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG10866-M-F from Sino Biological Species Human

Human CHRDL1 Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG10866-M-N from Sino Biological Species Human Accession NM_001143981.1

Human Chordin-Like 1/CHRDL1 Gene ORF cDNA clone expression plasmid, N-His tag - HG10866-NH from Sino Biological Species Human

Human Chordin-Like 1/CHRDL1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG10866-NY from Sino Biological Species Human

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