CHRDL1

Gene Symbol	CHRDL1
Entrez Gene	91851
Alt Symbol	CHL, MGC1, MGCN, NRLN1, VOPT, dA141H5.1
Species	Human
Gene Type	protein-coding
Description	chordin-like 1
Other Description	chordin-like protein 1|neuralin 1|neuralin-1|neurogenesin-1|ventroptin
Swissprots	Q539E4 B1AKD0 Q9Y3H7 Q9BU40 E9PGS5 D3DUY6 B4DMP3
Accessions	EAX02655 EAX02656 EAX02657 Q9BU40 AA057564 AB209548 BAD92785 AK092245 BAG52508 AK293106 BAF85795 AK297563 BAG59955 AK312270 AY608914 AAU25841 BC002909 AAH02909 BP377491 DC404314 XM_005262221 XP_005262278 XM_005262222 XP_005262279 XM_005262223 XP_005262280 XM_005262224 XP_005262281 NM_001143981 NP_001137453 NM_001143982 NP_001137454 NM_001143983 NP_001137455 NM_145234 NP_660277
Function	Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation (By similarity). May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development. {ECO:0000250, ECO:0000269|PubMed:18587495, ECO:0000269|PubMed:22284829}.
Subcellular Location	Secreted {ECO:0000305}.
Tissue Specificity	Expressed in the developing cornea and in the eye anterior segment in addition to the retina. Differentially expressed in the fetal brain. There is high expression in cerebellum and neocortex. Expressed in retinal pericytes. {ECO:0000269|PubMed:18587495, ECO:0000269|PubMed:22284829}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CHRDL1 full length protein - ab164881 from Abcam Category Protein Source Wheat germ Species Human

Human CHRDL1 protein fragment - ab164882 from Abcam Category Protein Source Wheat germ Species Human

CHRDL1 Antibody Blocking Peptide - LS-E389 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Chordin-like 1/CHRDL1 Partial Recombinant Protein - H00091851-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human Chordin-like 1/CHRDL1 Protein - H00091851-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CHRDL1-Antibody-N-term-Blocking-peptide - BP10667a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Chordin-Like 1 - 1808-NR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Glu22-Cys450, with a C-terminal 10-His tag

Recombinant Human Chordin-Like 1, CF - 1808-NR-050/CF from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Glu22-Cys450, with a C-terminal 10-His tag

CHRDL1 - H00091851-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CHRDL1 - H00091851-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CHRDL1 - H00091851-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CHRDL1 - H00091851-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CHRDL1 fusion protein - ag7549 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CHRDL1, His tagged - CHRDL1-3188H from Creative Biomart Category Protein Source Human Cells Species Human

Recombinant Human Chordin-Like 1, His-tagged - CHRDL1-3189H from Creative Biomart Category Protein Source Mouse NSO Cells

Recombinant Human CHRDL1, GST-tagged - CHRDL1-11202H from Creative Biomart Category Protein Source E.coli Species Human

CHRDL1 - PN201306 from Elabscience Category Protein Prices $225.00, $475.00 Sizes 10 μg, 50 μg Source Human Cells Species Human

Recombinant Chordin Like Protein 1 (CHRDL1) - RPF625Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Chordin Like Protein 1 (CHRDL1) - RPF625Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Chordin Like Protein 1 (CHRDL1) - RPF625Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Chordin-like protein 1(CHRDL1) - CSB-YP866283HU CSB-EP866283HU CSB-BP866283HU CSB-MP866283HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Chordin-Like 1 Protein - 1808-NR from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Glu22-Cys450, with a C-terminal 10-His tag Species Human

Recombinant Human Chordin-Like 1 Protein, CF - 1808-NR/CF from R&D Systems Category Protein Prices $329.00 Sizes 50 µg Source Mouse myeloma cell line, NS0-derived Glu22-Cys450, with a C-terminal 10-His tag Species Human

Chordin-like 1/CHRDL1 Recombinant Protein Antigen - NBP1-84486PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Chordin-like 1/CHRDL1 Recombinant Protein Antigen - NBP1-84485PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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