HCAR3

Gene Symbol	HCAR3
Entrez Gene	8843
Alt Symbol	GPR109B, HCA3, HM74, PUMAG, Puma-g
Species	Human
Gene Type	protein-coding
Description	hydroxycarboxylic acid receptor 3
Other Description	G protein-coupled receptor 109B|G-protein coupled receptor 109B|G-protein coupled receptor HM74|G-protein coupled receptor HM74B|GTP-binding protein|hydroxy-carboxylic acid receptor 3|niacin receptor 2|nicotinic acid receptor 2|putative chemokine receptor
Swissprots	A8K4G5 Q8NGE4 E9PI97 P49019 B2R830
Accessions	ABX64359 BAC06083 EAW98335 EAW98336 P49019 AK290930 BAF83619 AK313212 BAG36027 BC038955 BC047891 AAH47891 BI908162 CB529340 CD366840 CU451507 D10923 BAA01721 DA948030 DA953971 R02740 NM_006018 NP_006009
Function	Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. {ECO:0000269|PubMed:12522134, ECO:0000269|PubMed:19561068}.
Subcellular Location	Cell membrane; Multi-pass membrane protein.
Tissue Specificity	Expression largely restricted to adipose tissue and spleen. {ECO:0000269|PubMed:12522134}.
Top Pathways	cAMP signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human HCAR3 / GPR109B / HM74 ELISA Kit (Sandwich ELISA) - LS-F9220 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.061 ng/ml Range 0.156-10 ng/ml

Human GPR109B ELISA Kit - abx151716 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

G Protein Coupled Receptor 109B (GPR109B), Human, ELISA Kit - SEG711Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.061ng/mL Range 0.156-10ng/mL

G Protein Coupled Receptor 109B (GPR109B), ELISA Kit - MBS2024214 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of GPR109B is typically less than 0.061ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates and calculating the corresponding concentration. Range 0.156-10ng/mL

ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) - SEG711Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for G Protein Coupled Receptor 109B (GPR109B) - SEG711Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.061ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA's were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

G Protein Coupled Receptor 109B (GPR109B), Human, ELISA Kit - DL-GPR109B-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.156-10 ng/mL

Human GPR109B ELISA Kit - abx571711 from Abbexa Category ELISA Kit Sensitivity 0.061 ng/ml Range 0.156 ng/ml - 10 ng/ml

Human GPR109B ELISA Kit - E015770 from Biobool Category ELISA Kit Sensitivity The minimum detectable dose of GPR109B is typically less than 0.061ng/mL. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined by adding

Human HCAR3 ELISA Kit - E085336 from Biobool Category ELISA Kit

GPR109B ELISA Kit (Human) (OKDD00291) - OKDD00291 from Aviva Systems Biology Category ELISA Kit Prices $580.00 Sizes 96 wells Sensitivity < 0.061 ng/mL Range 0.156-10 ng/mL

G Protein Coupled Receptor 109B (GPR109B), ELISA Kit - MBS455234 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.061ng/mL Range 0.156-10ng/mL

G Protein Coupled Receptor 109B (GPR109B), ELISA Kit - MBS9370724 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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