Gene Symbol | GZMM |
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Entrez Gene | 3004 |
Alt Symbol | LMET1, MET1 |
Species | Human |
Gene Type | protein-coding |
Description | granzyme M (lymphocyte met-ase 1) |
Other Description | HU-Met-1|Met-1 serine protease|granzyme M|lymphocyte met-ase 1|met-ase|natural killer cell granular protease |
Swissprots | P51124 |
Accessions | AAA57257 AAA57262 EAW61189 P51124 BC025701 AAH25701 CD366947 CR991101 HQ257986 ADR82740 L23134 AAA59582 NM_001258351 NP_001245280 NM_005317 NP_005308 |
Function | Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. {ECO:0000269|PubMed:18523284, ECO:0000269|PubMed:20406824}. |
Subcellular Location | Secreted. Cytoplasmic granule. Note=Granules of large granular lymphocytes. |
Tissue Specificity | Highly and constitutively expressed in activated natural killer (NK) cells. {ECO:0000269|PubMed:18523284}. |
Human GZMM full length protein - ab158624 from Abcam
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Human GZMM protein fragment - ab158625 from Abcam
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GZMM / Granzyme M Antibody Blocking Peptide - LS-E8464 from LifeSpan Bioscience
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Recombinant Human Granzyme M Protein - H00003004-P01 from Novus Biologicals
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Recombinant Human Granzyme M Protein - H00003004-Q01 from Novus Biologicals
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GZMM-Antibody-Center-Blocking-Peptide - BP6792c from Abgent, a WuXi AppTec company
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Granzyme M protein - 80R-4194E from Fitzgerald
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Human Granzyme M Protein - abx066913 from Abbexa
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Granzyme M ( GZMM) - H00003004-P01-02 from Acris Antibodies
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Granzyme M ( GZMM) - H00003004-Q01-10 from Acris Antibodies
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Granzyme M ( GZMM) - H00003004-Q01-25 from Acris Antibodies
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Granzyme M (GZMM), Human - 20-6666 from ARP American Research Products
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GZMM fusion protein - ag3982 from Proteintech Group
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GZMM fusion protein - Ag14402 from Proteintech Group
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Recombinant Human Human Granzyme M/GZMM - BP001416-C965 from Syd Labs
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Recombinant Human GZMM, His-tagged - GZMM-97H from Creative Biomart
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Recombinant Human GZMM, His-tagged - GZMM-98H from Creative Biomart
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Recombinant Granzyme M (GZMM) - RPA431Hu01 from Uscn Life Science Inc.
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Recombinant Granzyme M (GZMM) - RPA431Mu01 from Uscn Life Science Inc.
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Recombinant Granzyme M (GZMM) - RPA431Mu02 from Uscn Life Science Inc.
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Recombinant Granzyme M (GZMM) - RPA431Ra01 from Uscn Life Science Inc.
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Recombinant Granzyme M (GZMM) - RPA431Po01 from Uscn Life Science Inc.
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Granzyme M Blocking Peptide - CBP3983 from Cohesion Biosciences
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Recombinant Granzyme M (GZMM) - RPA431Hu01 from Cloud-clone
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Recombinant Human Granzyme M(GZMM) - CSB-YP010085HU CSB-EP010085HU CSB-BP010085HU CSB-MP010085HU from Cusabio
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