GZMM

Gene Symbol GZMM
Entrez Gene 3004
Alt Symbol LMET1, MET1
Species Human
Gene Type protein-coding
Description granzyme M (lymphocyte met-ase 1)
Other Description HU-Met-1|Met-1 serine protease|granzyme M|lymphocyte met-ase 1|met-ase|natural killer cell granular protease
Swissprots P51124
Accessions AAA57257 AAA57262 EAW61189 P51124 BC025701 AAH25701 CD366947 CR991101 HQ257986 ADR82740 L23134 AAA59582 NM_001258351 NP_001245280 NM_005317 NP_005308
Function Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells. {ECO:0000269|PubMed:18523284, ECO:0000269|PubMed:20406824}.
Subcellular Location Secreted. Cytoplasmic granule. Note=Granules of large granular lymphocytes.
Tissue Specificity Highly and constitutively expressed in activated natural killer (NK) cells. {ECO:0000269|PubMed:18523284}.

granzyme M CRISPR/Cas9 KO Plasmid (h) - sc-408484 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M HDR Plasmid (h) - sc-408484-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M Double Nickase Plasmid (h) - sc-408484-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M Double Nickase Plasmid (h2) - sc-408484-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M CRISPR Activation Plasmid (h) - sc-408484-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M CRISPR Activation Plasmid (h2) - sc-408484-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M Lentiviral Activation Particles (h) - sc-408484-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M Lentiviral Activation Particles (h2) - sc-408484-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

granzyme M siRNA (h) - sc-60761 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

granzyme M shRNA Plasmid (h) - sc-60761-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

granzyme M shRNA (h) Lentiviral Particles - sc-60761-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Granzyme M RNAi - H00003004-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU044151 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9830 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9830 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GZMM siRNA (Human) - CRH2039 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GZMM - MBS827231 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human GZMM (NM_005317.3) - SHH309706 from Creative biogene

Category siRNA
Species Reactivities Human

Human GZMM siRNA - orb262541 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GZMM shRNA Plasmid (Human) - CHH2039 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GZMM miRNA 3'UTR clone - MiUTR3H-03258 from Creative biogene

Species Reactivities Human
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