GADD45A

Gene Symbol GADD45A
Entrez Gene 1647
Alt Symbol DDIT1, GADD45
Species Human
Gene Type protein-coding
Description growth arrest and DNA-damage-inducible, alpha
Other Description DDIT-1|DNA damage-inducible transcript 1 protein|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|growth arrest and DNA damage-inducible protein GADD45 alpha|growth arrest and DNA-damage-inducible 45 alpha
Swissprots Q5TCA8 Q5TCA7 P24522
Accessions AAA72045 AAM88884 CBX53896 EAX06487 EAX06488 P24522 AK314991 BAG37487 AM393439 CAL38317 BC011757 AAH11757 BU629410 DQ008445 AAY25021 DQ893229 ABM84155 DQ896558 ABM87557 EF581092 ABQ52427 EF614238 M60974 AAA35863 NM_001199741 NP_001186670 NM_001199742 NP_001186671 NM_001924 NP_001915
Function In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. {ECO:0000250}.
Subcellular Location Nucleus {ECO:0000269|PubMed:7973727}.
Top Pathways Cell cycle, p53 signaling pathway, MAPK signaling pathway

GADD45 alpha (D17E8) Rabbit mAb - 4632 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D17E8
Western blot analysis of extracts from various cell lines and tissues using GADD45 alpha (D17E8) Rabbit mAb.

GADD45 α Antibody - 3518 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HeLa cells, untreated or treated with UV or doxirubicin, using GADD45 α Antibody.

GADD 45α (4T-27) - sc-796 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GADD 45α (4T-27): sc-796. Western blot analysis of GADD 45α transfected COS cells.

GADD 45α (H-165) - sc-797 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
GADD 45α (H-165): sc-797. Immunofluorescence staining of methanol-fixed GADD 45α-transfected COS cells showing nuclear localization.

GADD 45α (C-6) - sc-48394 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GADD 45α (C-6): sc-48394. Western blot analysis of GADD 45α expression in control (A) and GADD 45a transfected COS (B) whole cell lysates.

GADD 45α (C-4) - sc-6850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
GADD 45α (C-4): sc-6850. Western blot analysis of control (A) and GADD 45α transfected (B) COS cells.

GADD 45α (C-20) - sc-792 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Western blot analysis of COS cells transfected with GADD 45α (A,B). Antibodies tested include GADD 45α (C-20): sc-792 (A) and GADD 45α (H-165): sc-797 (B).

Anti-GADD45A antibody - ab54740 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing Jurkat cells stained with ab54740 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab54740, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was an anti-mouse Alexa Fluor® 488 (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-GADD45A antibody - ab203090 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-GADD45A antibody (ab203090) at 1/200 dilutionLane 1 : Rat brain lysateLane 2 : Rat kidney lysateSecondaryGoat Anti-Rabbit IgG Antibody (H+L), HRP at 1/3000 dilution

Anti-GADD45A antibody - ab112485 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GADD45A antibody - ab166669 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-GADD45A antibody (ab166669) at 1/1000 dilution + Mouse brain total cell extract

Anti-GADD45A antibody - Aminoterminal end - ab76664 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-GADD45A antibody - Aminoterminal end (ab76664) at 1/50 dilution + Y79 cell line lysates at 35 µg

Anti-GADD45A / GADD45 Antibody - LS-C129203 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal

Anti-GADD45A / GADD45 Antibody (clone 3D12) - LS-C197034 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D12

Anti-GADD45A / GADD45 Antibody - LS-C307629 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-GADD45A / GADD45 Antibody (aa1-25) - LS-C121222 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GADD45A / GADD45 Antibody (aa1-165) - LS-C311706 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GADD45A / GADD45 Antibody (aa1-165) - LS-C311713 from LifeSpan Bioscience

Prices $250.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GADD45A / GADD45 Antibody - LS-C341349 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-GADD45A / GADD45 Antibody (aa129-143) - LS-C312566 from LifeSpan Bioscience

Prices $305.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
WB of GADD45A / GADD45 antibody. Lane 1: M453 Cell Lysate. Lane 2: M231 Cell Lysate. Lane 3: HELA Cell Lysate. Lane 4: RAJI Cell Lysate. Lane 5: SW620 Cell Lysate.

Anti-GADD45A / GADD45 Antibody (clone 1C9) - LS-C338484 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GADD45A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GADD45A.

Anti-GADD45A / GADD45 Antibody (clone 2B7) - LS-C338488 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2B7
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GADD45A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GADD45A.

Anti-GADD45A / GADD45 Antibody (aa90-139) - LS-C135733 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GADD45A antibody LS-C135733 Western blot of Fetal Heart lysate.

Anti-GADD45A / GADD45 Antibody - LS-C335104 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of COLO 320 cells tissue, using GADD45A antibody.

Anti-GADD45A / GADD45 Antibody - LS-C331696 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded human esophagus using GADD45A antibody at dilution of 1:100 (400x lens).
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