GADD45A

Gene Symbol	GADD45A
Entrez Gene	1647
Alt Symbol	DDIT1, GADD45
Species	Human
Gene Type	protein-coding
Description	growth arrest and DNA-damage-inducible, alpha
Other Description	DDIT-1|DNA damage-inducible transcript 1 protein|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|growth arrest and DNA damage-inducible protein GADD45 alpha|growth arrest and DNA-damage-inducible 45 alpha
Swissprots	Q5TCA8 Q5TCA7 P24522
Accessions	AAA72045 AAM88884 CBX53896 EAX06487 EAX06488 P24522 AK314991 BAG37487 AM393439 CAL38317 BC011757 AAH11757 BU629410 DQ008445 AAY25021 DQ893229 ABM84155 DQ896558 ABM87557 EF581092 ABQ52427 EF614238 M60974 AAA35863 NM_001199741 NP_001186670 NM_001199742 NP_001186671 NM_001924 NP_001915
Function	In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. {ECO:0000250}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:7973727}.
Top Pathways	Cell cycle, p53 signaling pathway, MAPK signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-GADD45A-cDNA-Clone - DC03187 from Abgent, a WuXi AppTec company Prices $222.75 Sizes 10 µg Species Human Accession BC011757

GADD45A - MBS1273313 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC011757

Human GADD45A ORF Clone(NM_001924.3) - CDCL164243 from Creative Biomart Species Human Accession NM_001924.3

Human GADD45A ORF clone - CDCL110319 from Creative Biomart Species Human Accession NM_001199741

Human GADD45A ORF clone - CDCL110320 from Creative Biomart Species Human Accession NM_001199741

Mouse GADD45A ORF clone - CDCL110321 from Creative Biomart Species Human Accession NM_001199741

Mouse GADD45A ORF clone - CDCL110322 from Creative Biomart Species Human Accession NM_001199741

Human GADD45A ORF clone - CDCL110323 from Creative Biomart Species Human Accession NM_001199741

Human GADD45A ORF clone - CDCL110324 from Creative Biomart Species Human Accession NM_001199741

Human GADD45A/DDIT1 Gene ORF cDNA clone in cloning vector - HG11156-M from Sino Biological Species Human

Human GADD45A Gene cDNA Clone (full-length ORF Clone), expression ready, FLAG-tagged - HG11156-M-F from Sino Biological Species Human Accession NM_001924.2

Human GADD45A Gene cDNA Clone (full-length ORF Clone), expression ready, untagged - HG11156-M-N from Sino Biological Species Human Accession NM_001924.2

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11156-CY from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11156-ACR from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG11156-ANR from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid - HG11156-UT from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11156-ACG from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11156-NY from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11156-NF from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, N-His tag - HG11156-NH from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11156-NM from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG11156-ANG from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11156-CF from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11156-CM from Sino Biological Species Human

Human GADD45A/DDIT1 Gene ORF cDNA clone expression plasmid, C-His tag - HG11156-CH from Sino Biological Species Human

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