Gene Symbol | GADD45A |
---|---|
Entrez Gene | 1647 |
Alt Symbol | DDIT1, GADD45 |
Species | Human |
Gene Type | protein-coding |
Description | growth arrest and DNA-damage-inducible, alpha |
Other Description | DDIT-1|DNA damage-inducible transcript 1 protein|DNA damage-inducible transcript-1|DNA-damage-inducible transcript 1|growth arrest and DNA damage-inducible protein GADD45 alpha|growth arrest and DNA-damage-inducible 45 alpha |
Swissprots | Q5TCA8 Q5TCA7 P24522 |
Accessions | AAA72045 AAM88884 CBX53896 EAX06487 EAX06488 P24522 AK314991 BAG37487 AM393439 CAL38317 BC011757 AAH11757 BU629410 DQ008445 AAY25021 DQ893229 ABM84155 DQ896558 ABM87557 EF581092 ABQ52427 EF614238 M60974 AAA35863 NM_001199741 NP_001186670 NM_001199742 NP_001186671 NM_001924 NP_001915 |
Function | In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase. {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:7973727}. |
Top Pathways | Cell cycle, p53 signaling pathway, MAPK signaling pathway |
Human GADD45A full length protein - ab172160 from Abcam
|
||||||||||
Human GADD45A full length protein - ab95348 from Abcam
|
||||||||||
Human GADD45A full length protein - ab117181 from Abcam
|
||||||||||
GADD45A / GADD45 Antibody Blocking Peptide - LS-E7095 from LifeSpan Bioscience
|
||||||||||
GADD45A / GADD45 Antibody Blocking Peptide - LS-E7096 from LifeSpan Bioscience
|
||||||||||
GADD45A / GADD45 Antibody Blocking Peptide - LS-E22032 from LifeSpan Bioscience
|
||||||||||
GADD45 alpha Protein - NBP1-44475 from Novus Biologicals
|
||||||||||
GADD45 alpha Partial Recombinant Protein - H00001647-Q01 from Novus Biologicals
|
||||||||||
Recombinant Human GADD45 alpha Protein - H00001647-P01 from Novus Biologicals
|
||||||||||
GADD45A-Antibody-C-term-Blocking-Peptide - BP2785b from Abgent, a WuXi AppTec company
|
||||||||||
GADD45A-Antibody-N-term-Blocking-Peptide - BP2785a from Abgent, a WuXi AppTec company
|
||||||||||
GADD45A Protein - GTX109587-pro from GeneTex
|
||||||||||
GADD45A Protein - GTX110705-pro from GeneTex
|
||||||||||
GADD45A Protein (OPPA02167) - OPPA02167 from Aviva Systems Biology
|
||||||||||
Human GADD45A protein - orb81132 from Biorbyt
|
||||||||||
Human GADD45A protein - orb244217 from Biorbyt
|
||||||||||
GADD45A Blocking Peptide - 33R-5403 from Fitzgerald
|
||||||||||
GADD45A protein (His tag) - 80R-1312 from Fitzgerald
|
||||||||||
GADD45A (1-165, His-tag) - AR09458PU-L from Acris Antibodies
|
||||||||||
GADD45A (1-165, His-tag) - AR09458PU-N from Acris Antibodies
|
||||||||||
GADD45A - H00001647-P01-10 from Acris Antibodies
|
||||||||||
GADD45A - H00001647-P01-25 from Acris Antibodies
|
||||||||||
GADD45A - H00001647-Q01-10 from Acris Antibodies
|
||||||||||
GADD45A - H00001647-Q01-25 from Acris Antibodies
|
||||||||||
DDIT-1, GADD45 alpha, GADD45A, Human, Recombinant - 19-CE65 from ARP American Research Products
|