NCOA1

Gene Symbol	NCOA1
Entrez Gene	8648
Alt Symbol	F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74
Species	Human
Gene Type	protein-coding
Description	nuclear receptor coactivator 1
Other Description	Hin-2 protein|PAX3/NCOA1 fusion protein|class E basic helix-loop-helix protein 74|renal carcinoma antigen NY-REN-52|steroid receptor coactivator-1
Swissprots	Q53SX3 Q13420 Q2T9G5 Q13071 O43792 O43793 Q6GVI5 O00150 Q7KYV3 Q15788
Accessions	AAX93184 ABS29266 EAX00746 EAX00747 EAX00748 Q15788 AJ000881 CAA04371 AJ000882 CAA04372 AK226063 AK290019 BAF82708 BC035976 BC111533 AAI11534 BC111534 AAI11535 BE675986 BF975824 CB047008 U19179 AAA64187 U40396 AAC50305 U59302 AAC50631 U90661 AAB50242 XM_005264625 XP_005264682 XM_005264626 XP_005264683 XM_005264627 XP_005264684 XM_005264628 XP_005264685 XM_011533141 XP_011531443 NM_003743 NP_003734 NM_147223 NP_671756 NM_147233 NP_671766
Function	Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3. {ECO:0000269|Pu
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981}.
Tissue Specificity	Widely expressed. {ECO:0000269|PubMed:15313887, ECO:0000269|PubMed:9427757}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Rabbit anti-SRC1 Antibody, Affinity Purified - PLA0093 from Sigma-Aldrich Prices $323.50 Sizes 100 µl

Nuclear receptor coactivator 1 (NCOA1), Human, ELISA Kit - E01N0540 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t

Nuclear receptor coactivator 1, NCOA1, Human, ELISA Kit - E0335h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7216394 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7246366 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7220828 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7205991 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7222673 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7240090 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7224748 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7248833 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7214803 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7206887 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Nuclear receptor coactivator 1 (NCOA1), ELISA Kit - MBS7204844 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human NCOA1 / SRC-1 ELISA Kit (Custom ELISA) - LS-F14333 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Pig NCOA1 / SRC-1 ELISA Kit (Custom ELISA) - LS-F14334 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse NCOA1 / SRC-1 ELISA Kit (Custom ELISA) - LS-F14332 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human Nuclear receptor coactivator 1 ELISA Kit - abx253813 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Human Nuclear receptor coactivator 1 ELISA Kit - EKE53577 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.056 ng/mL Range 0.156-10 ng/mL

NCOA1 - EKH1714 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Human NCOA1 ELISA Kit - E026963 from Biobool Category ELISA Kit Sensitivity <0.094ng/ml

NCOA1 ELISA Kit (Human) (OKEH04299) - OKEH04299 from Aviva Systems Biology Category ELISA Kit Prices $596.00 Sizes 96 wells Sensitivity < 0.07 ng/mL Range 0.15 - 10 ng/mL

anti-NCOA1 / SRC1 antibody [SRC01 (GT12)] - ARG62626 from Arigo Biolaboratories Category ELISA Kit

Human Nuclear receptor coactivator 1 (NCOA1) ELISA Kit - AE31562HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t

Nuclear receptor coactivator 1, ELISA Kit - MBS289039 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.156-10 ng/mL

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