Gene Symbol | LTC4S |
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Entrez Gene | 4056 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | leukotriene C4 synthase |
Other Description | LTC4 synthase |
Swissprots | Q9UC73 Q9UD18 Q8N6P0 Q16873 |
Accessions | AAB06723 AAC50476 EAW53796 EAW53797 EAW53798 EAW53799 Q16873 AI480325 AK312033 BAG34970 BC029498 AAH29498 BI597970 BI819419 DQ890962 ABM81888 DQ894134 ABM85060 U09353 AAA20467 U11552 AAA50555 NM_145867 NP_665874 |
Function | Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4. |
Subcellular Location | Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected in lung, platelets and the myelogenous leukemia cell line KG-1 (at protein level). LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells and platelets. {ECO:0000269|PubMed:7599836}. |
Top Pathways | Arachidonic acid metabolism |
Human LTC4S full length protein - ab158833 from Abcam
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LTC4S / LTC4 Synthase Antibody Blocking Peptide - LS-E17740 from LifeSpan Bioscience
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LTC4S / LTC4 Synthase Antibody Blocking Peptide - LS-E9656 from LifeSpan Bioscience
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Recombinant Human LTC4S Protein - H00004056-P01 from Novus Biologicals
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LTC4S-Antibody-N-term-Blocking-Peptide - BP8584a from Abgent, a WuXi AppTec company
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LTC4S Blocking Peptide - 33R-6126 from Fitzgerald
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LTC4 synthase / LTC4S - H00004056-P01-10 from Acris Antibodies
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LTC4 synthase / LTC4S - H00004056-P01-25 from Acris Antibodies
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LTC4S fusion protein - Ag14202 from Proteintech Group
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LTC4S fusion protein - ag14559 from Proteintech Group
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Recombinant Human LTC4S, His tagged - LTC4S-923H from Creative Biomart
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Human LTC4S / LTC4 synthase Protein (His Tag) - 11622-H08B-20 from Sino Biological
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LTC4 synthase / LTC4S - TP306062 from Acris Antibodies
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Recombinant Human LTC4S / LTC4 synthase Protein (His tag) - PKSH031060 from Elabscience
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LTC4S Peptide, Human - M34GP08985H from Creative Peptides
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Human LTC4S / LTC4 synthase Protein (His Tag) - 11622-H08B from ABclonal
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Leukotriene C4 synthase (LTC4S), Recombinant Protein - MBS7019622 from MyBioSource
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LTC4S / LTC4 synthase, Recombinant Protein - MBS2545720 from MyBioSource
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