Gene Symbol | LTC4S |
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Entrez Gene | 4056 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | leukotriene C4 synthase |
Other Description | LTC4 synthase |
Swissprots | Q9UC73 Q9UD18 Q8N6P0 Q16873 |
Accessions | AAB06723 AAC50476 EAW53796 EAW53797 EAW53798 EAW53799 Q16873 AI480325 AK312033 BAG34970 BC029498 AAH29498 BI597970 BI819419 DQ890962 ABM81888 DQ894134 ABM85060 U09353 AAA20467 U11552 AAA50555 NM_145867 NP_665874 |
Function | Catalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4. |
Subcellular Location | Nucleus outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Tissue Specificity | Detected in lung, platelets and the myelogenous leukemia cell line KG-1 (at protein level). LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells and platelets. {ECO:0000269|PubMed:7599836}. |
Top Pathways | Arachidonic acid metabolism |
LTC 4 synthase (Y-13)-R - sc-22566-R from Santa Cruz Biotechnology
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LTC 4 synthase (S-18)-R - sc-22564-R from Santa Cruz Biotechnology
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Anti-LTC4S antibody - ab91507 from Abcam
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus, APC) - LS-C219905 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus, AP) - LS-C219907 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus, Biotin) - LS-C219910 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus, FITC) - LS-C219911 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus, Azide-free, HRP) - LS-C219912 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus, PE) - LS-C219913 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus) - LS-C327759 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus) - LS-C135219 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (N-Terminus) - LS-C82553 from LifeSpan Bioscience
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Anti-LTC4S / LTC4 Synthase Antibody (aa29-55) - LS-C163918 from LifeSpan Bioscience
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LTC4S Antibody - NBP1-69315 from Novus Biologicals
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Anti-LTC4S antibody produced in rabbit - AV49035 from Sigma-Aldrich
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LTC4S Antibody (OAED00035) - OAED00035 from Aviva Systems Biology
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LTC4S antibody - N-terminal region (ARP49035_P050) - ARP49035_P050 from Aviva Systems Biology
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LTC4S Antibody - N-terminal region (ARP49035_T100) - ARP49035_T100 from Aviva Systems Biology
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LTC4S-Antibody-N-term - AP8584a from Abgent, a WuXi AppTec company
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LTC4S Antibody - N-terminal region (OAAB05176) - OAAB05176 from Aviva Systems Biology
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LTC4S antibody, N-term - GTX81159 from GeneTex
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LTC4S antibody - 70R-8802 from Fitzgerald
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LTC4S antibody - 70R-1852 from Fitzgerald
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LTC4S antibody - orb185084 from Biorbyt
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LTC4S Antibody - abx034009 from Abbexa
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