PIK3AP1

Gene Symbol	PIK3AP1
Entrez Gene	118788
Alt Symbol	BCAP
Species	Human
Gene Type	protein-coding
Description	phosphoinositide-3-kinase adaptor protein 1
Other Description	B cell adaptor protein|B-cell adapter for phosphoinositide 3-kinase|B-cell phosphoinositide 3-kinase adapter protein 1|phosphoinositide 3-kinase adapter protein 1
Swissprots	Q8NAC8 Q8N6J6 Q5VXJ9 Q5TB56 Q6ZUJ8
Accessions	CCQ77684 EAW49968 EAW49969 Q6ZUJ8 AI826732 AK092883 BAC03996 AK122584 BAC56925 AK125635 BAC86227 AM393069 CAL37947 BC029917 AAH29917 BX648550 CB990570 XM_005269498 XP_005269555 XM_005269499 XP_005269556 XM_011539248 XP_011537550 XM_011539249 XP_011537551 NM_152309 NP_689522
Function	Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL. {ECO:0000269|PubMed:15893754}.
Subcellular Location	Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue Specificity	Expressed in natural killer (NK) cells. {ECO:0000269|PubMed:18337558}.
Top Pathways	B cell receptor signaling pathway, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PIK3AP1 full length protein - ab165145 from Abcam Category Protein Source Wheat germ Species Human

Human PIK3AP1 protein fragment - ab165146 from Abcam Category Protein Source Wheat germ Species Human

BCAP / PHF11 Antibody Blocking Peptide - LS-E12412 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCAP / PHF11 Antibody Blocking Peptide - LS-E14153 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCAP / PIK3AP1 Antibody Blocking Peptide - LS-E2001 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BCAP/PIK3AP1 Partial Recombinant Protein - H00118788-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human BCAP/PIK3AP1 Protein - H00118788-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

PIK3AP1-Antibody-C-term-Blocking-peptide - BP12861b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PIK3AP1 - H00118788-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

PIK3AP1 - H00118788-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

PIK3AP1 - H00118788-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

PIK3AP1 fusion protein - ag13404 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) - RPJ836Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) - RPJ836Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) - RPJ836Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Phosphoinositide 3-kinase adapter protein 1(PIK3AP1) ,partial - CSB-YP747806HU CSB-EP747806HU CSB-BP747806HU CSB-MP747806HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1), partial, Recombinant Protein - MBS1335961 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Phosphoinositide-3-Kinase Adaptor Protein 1, Recombinant Protein - MBS2031798 from MyBioSource Category Protein Prices $185.00, $380.00, $585.00 Sizes 10 µg, 50 µg, 100 µg Source Prokaryotic expression Species Human

BCAP/PIK3AP1 Recombinant Protein Antigen - NBP2-38413PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

PIK3AP1 Peptide, Human - M34GP11778H from Creative Peptides Category Peptide Source Synthetic. Species Human

PIK3AP1 Recombinant Protein (OPCD06176) - OPCD06176 from Aviva Systems Biology Category Protein Source E.coli Species Human

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