RFK

Gene Symbol	RFK
Entrez Gene	55312
Alt Symbol	RIFK
Species	Human
Gene Type	protein-coding
Description	riboflavin kinase
Other Description	0610038L10Rik|ATP:riboflavin 5'-phosphotransferase|flavokinase
Swissprots	Q969G6 Q9NUT7 Q5JSG9
Accessions	EAW62578 EAW62579 Q969G6 AF038172 AK002011 BAA92033 AK123933 AK307079 AK315734 BAG38089 BC007069 AAH07069 BF979572 DA154523 DB499473 DB531307 NM_018339 NP_060809
Function	Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase. {ECO:0000269|PubMed:19641494}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Detected in brain, placenta and urinary bladder.
Top Pathways	Riboflavin metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RFK Gene cDNA Clone - orb145058 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-RFK-cDNA-Clone - DC02084 from Abgent, a WuXi AppTec company Prices $210.60 Sizes 10 µg Species Human Accession NM_018339

RFK - MBS1278447 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC007069

Human RFK ORF Clone(NM_018339.5) - CDCL173564 from Creative Biomart Species Human Accession NM_018339.5

Human Flavokinase / RFK Gene ORF cDNA clone in cloning vector - HG13881-G from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, N-HA tag - HG13881-NY from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13881-NM from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13881-CF from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13881-CM from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13881-ACR from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13881-ANR from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, C-HA tag - HG13881-CY from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, N-His tag - HG13881-NH from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid - HG13881-UT from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13881-ANG from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13881-ACG from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, C-His tag - HG13881-CH from Sino Biological Species Human

Human Flavokinase / RFK Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13881-NF from Sino Biological Species Human

human RFK ORF clone (NM_018339.5) - CDCH073134 from Creative biogene Species Human

Human RFK ORF Clone (BC007069) - CDCS414755 from Creative biogene Species Human Accession Q969G6

Human RFK ORF clone (BC007069.1) - CDCB159556 from Creative biogene Species Human

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