RFK

Gene Symbol	RFK
Entrez Gene	55312
Alt Symbol	RIFK
Species	Human
Gene Type	protein-coding
Description	riboflavin kinase
Other Description	0610038L10Rik|ATP:riboflavin 5'-phosphotransferase|flavokinase
Swissprots	Q969G6 Q9NUT7 Q5JSG9
Accessions	EAW62578 EAW62579 Q969G6 AF038172 AK002011 BAA92033 AK123933 AK307079 AK315734 BAG38089 BC007069 AAH07069 BF979572 DA154523 DB499473 DB531307 NM_018339 NP_060809
Function	Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase. {ECO:0000269|PubMed:19641494}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Detected in brain, placenta and urinary bladder.
Top Pathways	Riboflavin metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RFK full length protein - ab89009 from Abcam Category Protein Source E. coli Species Human

RFK Antibody Blocking Peptide - LS-E23578 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

RFK Recombinant Protein - H00055312-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Species Human

RFK Partial Recombinant Protein - H00055312-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human RFK Protein - NBP1-30190 from Novus Biologicals Category Protein Prices $349.00 Sizes 100 µg Species Human

Flavokinase Protein (OPPA01990) - OPPA01990 from Aviva Systems Biology Category Protein Prices $100.00 Sizes 5 µg Source E. Coli

Human Flavokinase protein - orb80807 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 5 μg, 20 μg Species Human

Human RIFK protein (His Tag) - orb139591 from Biorbyt Category Protein Prices $323.00, $646.00 Sizes 20 μg, 100 μg Source E. coli Species Human

Riboflavin kinase protein (His tag) - 80R-1176 from Fitzgerald Category Protein Prices $340.00 Sizes 100 µg Source E.coli

Riboflavin kinase (RFK) (1-162, His-tag) - AR09239PU-L from Acris Antibodies Category Protein Prices $1,010.00 Sizes 500 µg Source E. coli Species Human

Riboflavin kinase (RFK) (1-162, His-tag) - AR09239PU-N from Acris Antibodies Category Protein Prices $410.00 Sizes 100 µg Source E. coli Species Human

Riboflavin kinase (RFK) - H00055312-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

Riboflavin kinase (RFK) - H00055312-P01-10 from Acris Antibodies Category Protein Prices $340.00 Sizes 10 µg Source in vitro transl. Species Human

Riboflavin kinase (RFK) - H00055312-P01-25 from Acris Antibodies Category Protein Prices $460.00 Sizes 25 µg Source in vitro transl. Species Human

Riboflavin kinase (RFK) - H00055312-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Riboflavin kinase (RFK) - H00055312-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Riboflavin Kinase, Human Recombinant - 228-10478-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Source Escherichia Coli. Species Human

Recombinant Human Flavokinase - 228-10478-2 from RayBiotech Category Protein Prices $189.00 Sizes 2 µg Source Escherichia Coli. Species Human

Recombinant Human Flavokinase - 228-10478-3 from RayBiotech Category Protein Prices $3,180.00 Sizes 3 µg Source Escherichia Coli. Species Human

Riboflavin kinase, 1-162 aa, Human, His-tagged, Recombinant, E.coli - 01-2140 from ARP American Research Products Category Protein Prices $189.00, $449.00, $1,089.00 Sizes 20 µg, 50 µg, 500 µg Source E.coli Species Human

RFK fusion protein - Ag8591 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

RFK fusion protein - Ag8582 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Flavokinase Human - PKPS-359 from NeoScientific Category Protein Prices $65.00, $169.00, $3,900.00 Sizes 5 µg, 20 µg, 1 mg Source Escherichia Coli. Species Human

Recombinant Human Riboflavin Kinase - BP000831-PKA-352 from Syd Labs Category Protein Prices $160.00, $3,000.00 Sizes 20 µg, 1 mg Source E. coli-derived. Species Human

Riboflavin kinase, 1-162 aa, Recombinant Protein - GWB-P1680C from Genway Biotech Category Protein Prices $400.00, $1,200.00 Sizes 100 μg, 500 μg Source E.coli Species Human

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