NGFR

Gene Symbol	NGFR
Entrez Gene	4804
Alt Symbol	CD271, Gp80-LNGFR, TNFRSF16, p75(NTR), p75NTR
Species	Human
Gene Type	protein-coding
Description	nerve growth factor receptor
Other Description	NGF receptor|TNFR superfamily, member 16|low affinity nerve growth factor receptor|low affinity neurotrophin receptor p75NTR|low-affinity nerve growth factor receptor|p75 ICD|tumor necrosis factor receptor superfamily member 16
Swissprots	B2R961 P08138 B4E096
Accessions	AAA36363 CAM36380 CBX53856 EAW94677 P08138 AK303278 BAG64358 AK313654 BAG36408 BC050309 AAH50309 BC052797 BQ639556 CK299927 DA115173 M14764 AAB59544 NM_002507 NP_002498
Function	Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver. {ECO:0000250, ECO:0000269|PubMed:14966521, ECO:0000269|PubMed:23785138}.
Subcellular Location	Membrane; Single-pass type I membrane protein.
Top Pathways	Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Rap1 signaling pathway, Transcriptional misregulation in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human p75 NGF Receptor protein fragment - ab157276 from Abcam Category Protein Prices $465.00 Sizes 50 µg Source HEK 293 cells Species Human

NGF Receptor (222 aa) - Fc Chimera - ab83678 from Abcam Prices $302.00 Sizes 25 µg Source HEK 293 cells Species Human

Human p75 NGF Receptor full length protein - ab131792 from Abcam Category Protein Source Wheat germ Species Human

NGF Receptor (209 aa) - Fc Chimera - ab83679 from Abcam Source HEK 293 cells Species Human

Human p75 NGF Receptor protein fragment - ab158995 from Abcam Category Protein Source Wheat germ Species Human

p75 NGF Receptor peptide (342-353) - ab45742 from Abcam Category Peptide Species Human

Rat p75 NGF Receptor peptide - ab38334 from Abcam Category Peptide

NGFR / CD271 Antibody Blocking Peptide - LS-E1751 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NGFR / CD271 Antibody Blocking Peptide - LS-E27767 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NGFR / CD271 Antibody Blocking Peptide - LS-E25887 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NGFR / CD271 Antibody Blocking Peptide - LS-E23084 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

p75NTR/NGF Receptor Protein - NBP1-46099 from Novus Biologicals Category Protein Prices $299.00 Sizes 25 µg Species Human

p75NTR/NGF Receptor Partial Recombinant Protein - H00004804-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

NGF R/TNFRSF16/p75NTR Recombinant Protein - H00004804-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg

NGF R/TNFRSF16/p75NTR Recombinant Protein - H00004804-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

CD271-Antibody-C-term-Blocking-peptide - BP12542b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

p75 NGF Receptor / CD271 blocking peptide - GTX89556-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Dog, Rat, Bovine

Recombinant Human NGF R/TNFRSF16 Fc Chimera - 367-NR-050 from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Recombinant Human NGF R/TNFRSF16 Fc Chimera, CF - 367-NR-050/CF from R&D Systems Category Protein Source Spodoptera frugiperda, Sf 21 (baculovirus)-derived

Human NGFR protein (His Tag) - orb139396 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

Human NGFR protein - orb139395 from Biorbyt Category Protein Prices $400.00, $612.00 Sizes 50 μg, 100 μg Source Human Cells Species Human

CD271 Blocking Peptide - abx063006 from Abbexa Category Peptide Species Human, Mouse, Rat, Bovine, Dog, Monkey, Pig

p75 NGF Receptor Peptide - AC21-0717-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

p75 NGF Receptor Peptide - AC21-2579-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CD271 / NGFR - H00004804-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

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