CYTH2

Gene Symbol CYTH2
Entrez Gene 9266
Alt Symbol ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like
Species Human
Gene Type protein-coding
Description cytohesin 2
Other Description ARF exchange factor|ARF nucleotide-binding site opener|CTC-273B12.8|PH, SEC7 and coiled-coil domain-containing protein 2|cytohesin-2|pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)|pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2)
Swissprots A8K8P0 Q8IXY9 Q92958 Q99418
Accessions EAW52349 EAW52350 EAW52351 Q99418 AB209573 BAD92810 AF318380 AAL55887 AK091443 AK292405 BAF85094 AK299590 BAG61522 BC004361 AAH04361 BC012771 BC035646 BC036615 BC038713 AAH38713 BC042153 BC047631 DC344850 DQ892565 ABM83491 DQ896856 ABM87855 HG510916 U59752 AAB17532 U70728 AAB09591 X99753 CAA68084 XM_006723472 XP_006723535 XM_006723473 XP_006723536 NM_004228 NP_004219 NM_017457 NP_059431
Function Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. {ECO:0000269|PubMed:17398095}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17398095}; Peripheral membrane protein {ECO:0000269|PubMed:17398095}. Cytoplasm {ECO:0000269|PubMed:17398095}. Note=Both isoform 1 and isoform 2 are recruited to the cell membrane through their association with ARL4A, ARL4C and ARL4D. They require also interaction with phosphoinositides for targeting to the plasma membrane.
Tissue Specificity Ubiquitous.
Top Pathways Endocytosis

Cytohesin-2 (CYTH2), Human, ELISA Kit - CSB-EL006468HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Cytohesin-2 (CYTH2), Human, ELISA Kit - E01C2265 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

CYTH2 (Human) IP-WB Antibody Pair - H00009266-PW1 from Acris Antibodies

Category Antibody Pair
Prices $610.00
Sizes 1 set

cytohesin 2, ELISA Kit - MBS917327 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Cytohesin 2 (CYTH2), ELISA Kit - MBS7226307 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Cytohesin-2(CYTH2) ELISA kit - CSB-EL006468HU from Cusabio

Category ELISA Kit
Sensitivity 2.34 pg/ml
Range 9.375 pg/ml-600 pg/ml

Human Cytohesin-2 (CYTH2) ELISA Kit - EKC33388 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 2.34 pg/ml
Range 9.375 pg/ml-600 pg/ml

Human CYTH2 ELISA Kit - E011142 from Biobool

Category ELISA Kit

anti-ARNO / cytohesin 2 antibody - ARG64382 from Arigo Biolaboratories

Category ELISA Kit

CYTH2 ELISA Kit (Human) (OKCA01189) - OKCA01189 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 2.34 pg/mL
Range 9.375 - 600 pg/mL
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