CYTH2

Gene Symbol	CYTH2
Entrez Gene	9266
Alt Symbol	ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like
Species	Human
Gene Type	protein-coding
Description	cytohesin 2
Other Description	ARF exchange factor|ARF nucleotide-binding site opener|CTC-273B12.8|PH, SEC7 and coiled-coil domain-containing protein 2|cytohesin-2|pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)|pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2)
Swissprots	A8K8P0 Q8IXY9 Q92958 Q99418
Accessions	EAW52349 EAW52350 EAW52351 Q99418 AB209573 BAD92810 AF318380 AAL55887 AK091443 AK292405 BAF85094 AK299590 BAG61522 BC004361 AAH04361 BC012771 BC035646 BC036615 BC038713 AAH38713 BC042153 BC047631 DC344850 DQ892565 ABM83491 DQ896856 ABM87855 HG510916 U59752 AAB17532 U70728 AAB09591 X99753 CAA68084 XM_006723472 XP_006723535 XM_006723473 XP_006723536 NM_004228 NP_004219 NM_017457 NP_059431
Function	Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. {ECO:0000269|PubMed:17398095}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17398095}; Peripheral membrane protein {ECO:0000269|PubMed:17398095}. Cytoplasm {ECO:0000269|PubMed:17398095}. Note=Both isoform 1 and isoform 2 are recruited to the cell membrane through their association with ARL4A, ARL4C and ARL4D. They require also interaction with phosphoinositides for targeting to the plasma membrane.
Tissue Specificity	Ubiquitous.
Top Pathways	Endocytosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CYTH2-Over-expression-Lysate - LY14101a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

PSCD2 293T Cell Transient Overexpression Lysate(Denatured) - H00009266-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CYTH2 overexpression lysate - LY413761 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CYTH2 293 Cell Lysate - 406619 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

Cytohesin 2 Overexpression Lysate (Denatured) - H00009266-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

Cytohesin 2 Overexpression Lysate (Native) - NBL1-14857 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

cytohesin-2 (h): 293T Lysate - sc-176453 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

CYTH2 Over-expression Lysate Product - GWB-B504FB from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Cytohesin 2 Overexpression Lysate (Denatured) - H00009266-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human CYTH2 Knockdown Stable Cell Line - CSC-DC003997 from Creative biogene Category Cell Line Species Human

Search more