CYTH2

Gene Symbol CYTH2
Entrez Gene 9266
Alt Symbol ARNO, CTS18, CTS18.1, PSCD2, PSCD2L, SEC7L, Sec7p-L, Sec7p-like
Species Human
Gene Type protein-coding
Description cytohesin 2
Other Description ARF exchange factor|ARF nucleotide-binding site opener|CTC-273B12.8|PH, SEC7 and coiled-coil domain-containing protein 2|cytohesin-2|pleckstrin homology, Sec7 and coiled-coil domains 2 (cytohesin-2)|pleckstrin homology, Sec7 and coiled/coil domains 2 (cytohesin-2)
Swissprots A8K8P0 Q8IXY9 Q92958 Q99418
Accessions EAW52349 EAW52350 EAW52351 Q99418 AB209573 BAD92810 AF318380 AAL55887 AK091443 AK292405 BAF85094 AK299590 BAG61522 BC004361 AAH04361 BC012771 BC035646 BC036615 BC038713 AAH38713 BC042153 BC047631 DC344850 DQ892565 ABM83491 DQ896856 ABM87855 HG510916 U59752 AAB17532 U70728 AAB09591 X99753 CAA68084 XM_006723472 XP_006723535 XM_006723473 XP_006723536 NM_004228 NP_004219 NM_017457 NP_059431
Function Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. {ECO:0000269|PubMed:17398095}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:17398095}; Peripheral membrane protein {ECO:0000269|PubMed:17398095}. Cytoplasm {ECO:0000269|PubMed:17398095}. Note=Both isoform 1 and isoform 2 are recruited to the cell membrane through their association with ARL4A, ARL4C and ARL4D. They require also interaction with phosphoinositides for targeting to the plasma membrane.
Tissue Specificity Ubiquitous.
Top Pathways Endocytosis

cytohesin-2 CRISPR/Cas9 KO Plasmid (h) - sc-403025 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 HDR Plasmid (h) - sc-403025-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 Double Nickase Plasmid (h) - sc-403025-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 Double Nickase Plasmid (h2) - sc-403025-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 CRISPR Activation Plasmid (h) - sc-403025-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 CRISPR Activation Plasmid (h2) - sc-403025-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 Lentiviral Activation Particles (h) - sc-403025-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 Lentiviral Activation Particles (h2) - sc-403025-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

cytohesin-2 siRNA (h) - sc-40468 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cytohesin-2 shRNA Plasmid (h) - sc-40468-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

cytohesin-2 shRNA (h) Lentiviral Particles - sc-40468-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Cytohesin 2 RNAi - H00009266-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU129861 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6900 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6900 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00321 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00321

CYTH2 siRNA (Human) - CRH6136 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Cytohesin 2 RNAi - H00009266-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

CYTH2 - MBS8229661 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CYTH2 (NM_004228.6) - SHH273917 from Creative biogene

Category siRNA
Species Reactivities Human

Human CYTH2 siRNA - orb266638 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CYTH2 shRNA Plasmid (Human) - CHH6136 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CYTH2 miRNA 3'UTR clone - MiUTR4H-TG02541 from Creative biogene

Species Reactivities Human
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