CNOT6L

Gene Symbol	CNOT6L
Entrez Gene	246175
Alt Symbol	CCR4b
Species	Human
Gene Type	protein-coding
Description	CCR4-NOT transcription complex, subunit 6-like
Other Description	CCR4-NOT transcription complex subunit 6-like|carbon catabolite repressor protein 4 homolog B
Swissprots	Q96LI5 Q9UF92
Accessions	EAX05818 EAX05819 Q96LI5 AK027214 AK058188 BAB71707 AK124855 AK303417 BAG64470 AK304397 BAG65232 AL133112 CAB61415 BC152816 AAI52817 DA043791 DB454180 XM_011531806 XP_011530108 XM_011531807 XP_011530109 XM_011531808 XP_011530110 XM_011531809 XP_011530111 XM_011531810 XP_011530112 NM_001286790 NP_001273719 NM_144571 NP_653172
Function	Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA. Its mRNA deadenylase activity can be inhibited by TOB1. Mediates cell proliferation and cell survival and prevents cellular senescence. {ECO:0000269|PubMed:17452450, ECO:0000269|PubMed:21233283}.
Subcellular Location	Cytoplasm. Nucleus.
Tissue Specificity	Highly expressed in placenta, skeletal muscle, pancreas, testis and leukocytes. Weakly expressed in heart, spleen and thymus. {ECO:0000269|PubMed:17452450}.
Top Pathways	RNA degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CCR4-NOT transcription complex subunit 6-like (CNOT6L), Human, ELISA Kit - E01C1862 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 100-2500pg/ml

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7216644 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7253269 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7211868 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7229533 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7220605 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7203467 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7211419 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7216815 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7242953 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7247327 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

CCR4-NOT transcription complex subunit 6-like (CNOT6L), ELISA Kit - MBS7221738 from MyBioSource Category ELISA Kit Prices $470.00, $675.00, $2,925.00, $5,490.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS062475 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS056596 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS086049 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ng/ml Range 0.625 ng/ml - 20 ng/ml

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS073263 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS073791 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS058965 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS048982 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS062061 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS067950 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS083058 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS074378 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS101770 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Carbon Catabolite Repression 4 Like Protein, ELISA Kit - MBS099219 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Search more