SRGAP1

Gene Symbol SRGAP1
Entrez Gene 57522
Alt Symbol ARHGAP13
Species Human
Gene Type protein-coding
Description SLIT-ROBO Rho GTPase activating protein 1
Other Description SLIT-ROBO Rho GTPase-activating protein 1|rho GTPase-activating protein 13
Swissprots Q9P2P2 Q9H8A3 Q7Z6B7
Accessions EAW97122 EAW97123 Q7Z6B7 AB037725 BAA92542 AK023899 AK025819 AK123684 BC006127 BC029919 BC053903 AAH53903 XM_005269042 XP_005269099 XM_011538580 XP_011536882 XM_011538581 XP_011536883 XM_011538582 XP_011536884 XM_011538583 XP_011536885 NM_020762 NP_065813
Function GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. {ECO:0000269|PubMed:11672528}.
Tissue Specificity Expressed in brain, lung, kidney, and testis. {ECO:0000269|PubMed:11672528}.
Top Pathways Axon guidance

SRGAP1 293T Cell Transient Overexpression Lysate(Denatured) - H00057522-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SRGAP1 overexpression lysate - LY412319 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

SRGAP1 Overexpression Lysate (Native) - NBP2-06611 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: SRGAP1 Overexpression Lysate (Adult Normal) [NBP2-06611] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SRGAP1.

SRGAP1 Overexpression Lysate (Denatured) - H00057522-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl

Panoply™ Human SRGAP1 Knockdown Stable Cell Line - CSC-DC015147 from Creative biogene

Category Cell Line
Species Human
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