SRGAP1

Gene Symbol SRGAP1
Entrez Gene 57522
Alt Symbol ARHGAP13
Species Human
Gene Type protein-coding
Description SLIT-ROBO Rho GTPase activating protein 1
Other Description SLIT-ROBO Rho GTPase-activating protein 1|rho GTPase-activating protein 13
Swissprots Q9P2P2 Q9H8A3 Q7Z6B7
Accessions EAW97122 EAW97123 Q7Z6B7 AB037725 BAA92542 AK023899 AK025819 AK123684 BC006127 BC029919 BC053903 AAH53903 XM_005269042 XP_005269099 XM_011538580 XP_011536882 XM_011538581 XP_011536883 XM_011538582 XP_011536884 XM_011538583 XP_011536885 NM_020762 NP_065813
Function GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. {ECO:0000269|PubMed:11672528}.
Tissue Specificity Expressed in brain, lung, kidney, and testis. {ECO:0000269|PubMed:11672528}.
Top Pathways Axon guidance

SRGAP1 CRISPR/Cas9 KO Plasmid (h) - sc-403408 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 HDR Plasmid (h) - sc-403408-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 Double Nickase Plasmid (h) - sc-403408-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 Double Nickase Plasmid (h2) - sc-403408-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 CRISPR Activation Plasmid (h) - sc-403408-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 CRISPR Activation Plasmid (h2) - sc-403408-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 Lentiviral Activation Particles (h) - sc-403408-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 Lentiviral Activation Particles (h2) - sc-403408-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

SRGAP1 siRNA (h) - sc-95789 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SRGAP1 shRNA Plasmid (h) - sc-95789-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

SRGAP1 shRNA (h) Lentiviral Particles - sc-95789-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU087291 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN20569 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20569 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SRGAP1 siRNA (Human) - CRJ1505 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SRGAP1 RNAi - H00057522-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SRGAP1 - MBS8226968 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SRGAP1 (NM_020762.2) - SHH417800 from Creative biogene

Category siRNA
Species Reactivities Human

SRGAP1 shRNA Plasmid (Human) - CHJ1505 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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