SRGAP1

Gene Symbol SRGAP1
Entrez Gene 57522
Alt Symbol ARHGAP13
Species Human
Gene Type protein-coding
Description SLIT-ROBO Rho GTPase activating protein 1
Other Description SLIT-ROBO Rho GTPase-activating protein 1|rho GTPase-activating protein 13
Swissprots Q9P2P2 Q9H8A3 Q7Z6B7
Accessions EAW97122 EAW97123 Q7Z6B7 AB037725 BAA92542 AK023899 AK025819 AK123684 BC006127 BC029919 BC053903 AAH53903 XM_005269042 XP_005269099 XM_011538580 XP_011536882 XM_011538581 XP_011536883 XM_011538582 XP_011536884 XM_011538583 XP_011536885 NM_020762 NP_065813
Function GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. {ECO:0000269|PubMed:11672528}.
Tissue Specificity Expressed in brain, lung, kidney, and testis. {ECO:0000269|PubMed:11672528}.
Top Pathways Axon guidance

Human SRGAP1 protein fragment - ab163577 from Abcam

Category Protein
Source Wheat germ
Species Human
ab163577 on a 12.5% SDS-PAGE stained with Coomassie Blue.

SRGAP1 Antibody Blocking Peptide - LS-E5314 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SRGAP1 Antibody Blocking Peptide - LS-E20972 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human SRGAP1 Protein - H00057522-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

SRGAP1-Antibody-Center-Blocking-Peptide - BP17794c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

SRGAP1 Blocking Peptide - 33R-1856 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

ARHGAP13 / SRGAP1 - H00057522-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

ARHGAP13 / SRGAP1 - H00057522-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SRGAP1 fusion protein - Ag14270 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PET28a
Species Human

SRGAP1 fusion protein - Ag14180 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

SRGAP1 fusion protein - ag4104 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human SRGAP1, His-tagged - SRGAP1-2950H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human SLIT-ROBO Rho GTPase-activating protein 1(SRGAP1) ,partial - CSB-YP770358HU CSB-EP770358HU CSB-BP770358HU CSB-MP770358HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

ARHGAP13 / SRGAP1 - TP308812 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
ARHGAP13 / SRGAP1

SRGAP1 Recombinant Protein Antigen - NBP2-13377PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

SRGAP1 Peptide, Human - M34GP15147H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

SLIT-ROBO Rho GTPase-activating protein 1 (SRGAP1), partial, Recombinant Protein - MBS1395705 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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