VASP

Gene Symbol	VASP
Entrez Gene	7408
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	vasodilator-stimulated phosphoprotein
Other Description	-
Swissprots	Q93035 P50552 B2RBT9 Q6PIZ1
Accessions	CAA67109 CAA67147 EAW57362 EAW57363 EAW57364 EAW57365 P50552 AK314812 BAG37336 AL556269 BC026019 AAH26019 BC038224 AAH38224 BG751094 BG825983 Z46389 CAA86523 XM_005259199 XP_005259256 XM_005259200 XP_005259257 NM_003370 NP_003361 NM_001008736
Function	Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin- bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. {ECO:0000269|PubMed:10087267, ECO:0000269|PubMed:10438535, ECO:0000269|PubMed:15939738, ECO:0000269|PubMed:17082196, ECO:0000269|PubMed:18559661}.
Subcellular Location	Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction {ECO:0000250}. Cell projection, lamellipodium membrane. Cell projection, filopodium membrane. Note=Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions. Localized along the sides of actin filaments throughout the peripheral cytoplasm under basal conditions. In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes).
Tissue Specificity	Highly expressed in platelets. {ECO:0000269|PubMed:7828592}.
Top Pathways	Focal adhesion, Leukocyte transendothelial migration, Fc gamma R-mediated phagocytosis, cGMP-PKG signaling pathway, Rap1 signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Mouse/Human/Rat VASP ELISA Kit (Cell-Based ELISA) - LS-F2378 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 0.156-10 ng/ml

Human VASP ELISA Kit (Sandwich ELISA) - LS-F7186 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.058 ng/ml Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-VASP (Ser157) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1108 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Mouse/Human/Rat Phospho-VASP (Ser238) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1646 from LifeSpan Bioscience Category ELISA Kit Prices $550.00 Sizes 1 plate Range 0.156-10 ng/ml

Rat VASP ELISA Kit (Sandwich ELISA) - LS-F9625 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.054 ng/ml Range 0.156-10 ng/ml

Human VASP ELISA Kit (Sandwich ELISA) - LS-F12926 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.156 Range 0.156-10 ng/ml

Human/Mouse/Rat Phospho-VASP (S157) Cell-Based ELISA - KCB8019 from R&D Systems Category ELISA Kit Prices $459.00 Sizes 1 kit

Vasodilator Stimulated Phosphoprotein (VASP), Human, ELISA Kit - SEC603Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.056ng/mL Range 0.156-10ng/mL

Vasodilator-stimulated phosphoprotein (VASP), Human, ELISA Kit - CSB-EL025797HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 15.6 pg/ml Range 62.5 pg/ml-4000 pg/ml

Vasodilator-stimulated phosphoprotein, VASP, Human, ELISA Kit - E9578h from ARP American Research Products Category ELISA Kit Prices $736.00 Sizes 96 t Range 0.156-10 ng/mL

VASP (Human) Matched Antibody Pair - H00007408-AP21 from Acris Antibodies Category Antibody Pair Prices $610.00 Sizes 1 set

VASP Colorimetric Cell-Based ELISA Kit - CB5716 from Assay Biotechnology Category ELISA Kit Prices $380.00, $760.00, $1,140.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

VASP (Phospho-Ser157) Colorimetric Cell-Based ELISA Kit - CBP1088 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

VASP (Phospho-Ser238) Colorimetric Cell-Based ELISA Kit - CBP1704 from Assay Biotechnology Category ELISA Kit Prices $480.00, $960.00, $1,440.00 Sizes 1 kit, 2 kits, 3 kits Range > 5000 Cells

Vasodilator Stimulated Phosphoprotein (VASP), ELISA Kit - MBS2019692 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.058ng/mL. Range 0.156-10ng/mL

Vasodilator Stimulated Phosphoprotein (VASP), ELISA Kit - MBS2000343 from MyBioSource Category ELISA Kit Prices $405.00, $605.00, $820.00, $3,375.00, $6,125.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.052ng/mL. Range 0.156-10ng/mL

vasodilator-stimulated phosphoprotein, ELISA Kit - MBS919987 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of human VASP is typically less than 15.6 pg/ml.The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 62.5 pg/ml -4000 pg/ml.

VASP, ELISA Kit - MBS2516270 from MyBioSource Category ELISA Kit Prices $410.00, $490.00, $2,040.00, $3,590.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/mL Range 0.156-10ng/mL

ELISA Kit for Vasodilator Stimulated Phosphoprotein (VASP) - SEC603Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.058ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

ELISA Kit for Vasodilator Stimulated Phosphoprotein (VASP) - SEC603Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.052ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human Vasodilator-stimulated phosphoprotein(VASP) ELISA kit - CSB-EL025797HU from Cusabio Category ELISA Kit Sensitivity 15.6 pg/ml Range 62.5 pg/ml-4000 pg/ml

Dog VASP ELISA Kit (Custom ELISA) - LS-F20482 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Bovine VASP ELISA Kit (Custom ELISA) - LS-F20481 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Mouse VASP ELISA Kit (Custom ELISA) - LS-F20483 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 0.156-10 ng/ml

Human Vasodilator-stimulated phosphoprotein ELISA Kit - abx251857 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

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