STAMBP

Gene Symbol STAMBP
Entrez Gene 10617
Alt Symbol AMSH, MICCAP
Species Human
Gene Type protein-coding
Description STAM binding protein
Other Description STAM-binding protein|associated molecule with the SH3 domain of STAM|endosome-associated ubiquitin isopeptidase
Swissprots D6W5H7 Q3MJE7 B5M0B6 O95630
Accessions AAX88908 CAC36455 CCQ43357 EAW99714 EAW99715 EAW99716 O95630 AF052135 AK023768 BC007682 AAH07682 BC065574 AAH65574 BC101467 AAI01468 BC101469 AAI01470 BF203378 BM478027 BQ929694 CX758449 DB477012 DN919763 DQ892616 ABM83542 DQ895856 ABM86782 DR158757 EU927390 ACH57452 U73522 AAD05037 XM_005264088 XP_005264145 XM_005264091 XP_005264148 XM_011532483 XP_011530785 XM_011532484 XP_011530786 XM_011532485 XP_011530787 XR_939651 NM_006463 NP_006454 NM_201647 NP_964010 NM_213622 NP_998787
Function Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways. {ECO:0000250, ECO:0000269|PubMed:10383417, ECO:0000269|PubMed:11483516, ECO:0000269|PubMed:15314065, ECO:0000269|PubMed:17261583, ECO:0000269|PubMed:23542699}.
Subcellular Location Nucleus. Membrane; Peripheral membrane protein. Cytoplasm. Early endosome.
Tissue Specificity Ubiquitously expressed.
Top Pathways Endocytosis

Human aMSH ELISA Kit - abx150641 from Abbexa

Category ELISA Kit
Sensitivity 5.22 pg/ml
Range 12.35 pg/ml - 1000 pg/ml

Alpha-Melanocyte Stimulating Hormone (aMSH), Human, ELISA Kit - CEA239Hu from ARP American Research Products

Category ELISA Kit
Prices $650.00
Sizes 96 t
Sensitivity 25pg/mL
Range 62.5-1,000pg/mL

alpha-MSH, AMSH, Human, ELISA Kit - E0239h from ARP American Research Products

Category ELISA Kit
Prices $596.00
Sizes 96 t
Range 1.56-100 ng/mL

Alpha-Melanocyte Stimulating Hormone, aMSH, Human, ELISA Kit - E-EL-H2414 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

Alpha-Melanocyte Stimulating Hormone, aMSH, Rabbit, ELISA Kit - E-EL-RB0997 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Alpha-Melanocyte Stimulating Hormone, aMSH, Chicken, ELISA Kit - E-EL-Ch2136 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Alpha-Melanocyte Stimulating Hormone, aMSH, Porcine, ELISA Kit - E-EL-P0611 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Alpha-Melanocyte Stimulating Hormone, aMSH, Guinea Pig, ELISA Kit - E-EL-GP1277 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Alpha-Melanocyte Stimulating Hormone, aMSH, Monkey, ELISA Kit - E-EL-MK0354 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

STAM binding protein, ELISA Kit - MBS9317410 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Alpha-Melanocyte Stimulating Hormone (aMSH), Human, ELISA Kit - DL-aMSH-Hu from ARP American Research Products

Category ELISA Kit
Prices $655.00
Sizes 96 t
Range 62.5-1,000 pg/mL

Human aMSH ELISA Kit - abx574158 from Abbexa

Category ELISA Kit
Sensitivity 25 pg/ml
Range 12.35 pg/ml - 1000 pg/ml

AMSH - EKH1584 from Nordic BioSite

Sensitivity 0.094ng/ml
Range 0.156-10ng/ml

AMSH ELISA Kit (Human) : 96 Wells (OKEH00326) - OKEH00326 from Aviva Systems Biology

Category ELISA Kit
Prices $420.00
Sizes 96 wells
Sensitivity < 0.6 ng/mL
Range 1.56 - 100 ng/mL

Custom Human AMSH/STAMBP ELISA - ELH-AMSH-1 from RayBiotech

Category ELISA Kit
Prices $627.00, $1,128.60, $2,508.00
Sizes 1 plate kit, 2 plate kit, 5 plate kit

Human AMSH ELISA Kit - E001676 from Biobool

Category ELISA Kit
Sensitivity <0.094ng/ml

Human STAMBP ELISA Kit - E036626 from Biobool

Category ELISA Kit

STAM-binding protein, ELISA Kit - MBS284170 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Custom Human STAMBP ELISA Kit - orb384466 from Biorbyt

Category ELISA Kit
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