Gene Symbol | AGBL4 |
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Entrez Gene | 84871 |
Alt Symbol | CCP6 |
Species | Human |
Gene Type | protein-coding |
Description | ATP/GTP binding protein-like 4 |
Other Description | ATP/GTP-binding protein-like 4|cytosolic carboxypeptidase 6 |
Swissprots | B4DG37 B3KT26 Q5VU57 |
Accessions | EAX06847 Q5VU57 AF075049 AK027348 BAB55053 AK094826 BAG52938 AK294394 BAG57648 AK294633 BAG57812 AK296221 BAG58944 BC035739 BC126383 AAI26384 BC144171 XM_006710986 XP_006711049 XM_011542308 XP_011540610 XM_011542309 XP_011540611 XM_011542310 XP_011540612 XM_011542311 XP_011540613 NM_032785 NP_116174 |
Function | Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. {ECO:0000250|UniProtKB:Q09LZ8}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q09LZ8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23085998}. Golgi apparatus {ECO:0000269|PubMed:23085998}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:23085998}. Note=Colocalizes with gamma-tubulin in the centrioles at interphase and dividing cells and with glutamylated tubulin in basal bodies of ciliated cells. {ECO:0000269|PubMed:23085998}. |
CCP6 (G-13) - sc-138892 from Santa Cruz Biotechnology
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CCP6 (N-14) - sc-138893 from Santa Cruz Biotechnology
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Anti-AGBL4 antibody - ab155314 from Abcam
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Anti-AGBL4 antibody - ab74451 from Abcam
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Anti-AGBL4 antibody - ab106733 from Abcam
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Anti-AGBL4 Antibody (aa431-480) - LS-C119893 from LifeSpan Bioscience
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Anti-AGBL4 Antibody (aa109-268) - LS-C178919 from LifeSpan Bioscience
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CBCP6 Antibody - NBP2-15729 from Novus Biologicals
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CBCP6 Antibody - NBP1-91754 from Novus Biologicals
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Anti-AGBL4, C-Terminal antibody produced in rabbit - SAB4503388 from Sigma-Aldrich
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Anti-AGBL4 antibody produced in rabbit - SAB2701429 from Sigma-Aldrich
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Anti-AGBL4 antibody produced in rabbit - HPA037994 from Sigma-Aldrich
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AGBL4 antibody [N2C3] - GTX119799 from GeneTex
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AGBL4 Antibody (OAAF03553) - OAAF03553 from Aviva Systems Biology
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AGBL4 antibody - orb78175 from Biorbyt
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AGBL4 antibody - orb77879 from Biorbyt
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AGBL4 antibody - orb226502 from Biorbyt
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CBCP6 antibody - 70R-35861 from Fitzgerald
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Anti-AGBL4 Antibody - AC11-0379 from Abcore
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AGBL4 Antibody - abx007999 from Abbexa
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AGBL4 Antibody - abx037279 from Abbexa
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AGBL4 Antibody - abx037280 from Abbexa
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AGBL4 Antibody - abx014414 from Abbexa
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AGBL4 / CCP6 antibody - H00084871-B01P from Acris Antibodies
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Anti-AGBL4 antibody - STJ91506 from St John's Laboratory Ltd
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