AGBL4

Gene Symbol AGBL4
Entrez Gene 84871
Alt Symbol CCP6
Species Human
Gene Type protein-coding
Description ATP/GTP binding protein-like 4
Other Description ATP/GTP-binding protein-like 4|cytosolic carboxypeptidase 6
Swissprots B4DG37 B3KT26 Q5VU57
Accessions EAX06847 Q5VU57 AF075049 AK027348 BAB55053 AK094826 BAG52938 AK294394 BAG57648 AK294633 BAG57812 AK296221 BAG58944 BC035739 BC126383 AAI26384 BC144171 XM_006710986 XP_006711049 XM_011542308 XP_011540610 XM_011542309 XP_011540611 XM_011542310 XP_011540612 XM_011542311 XP_011540613 NM_032785 NP_116174
Function Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. {ECO:0000250|UniProtKB:Q09LZ8}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q09LZ8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23085998}. Golgi apparatus {ECO:0000269|PubMed:23085998}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:23085998}. Note=Colocalizes with gamma-tubulin in the centrioles at interphase and dividing cells and with glutamylated tubulin in basal bodies of ciliated cells. {ECO:0000269|PubMed:23085998}.

Human AGBL4 protein fragment - ab127321 from Abcam

Category Protein
Prices $364.00
Sizes 50 µg
Source E. coli
Species Human

AGBL4 Blocking Peptide - abx064016 from Abbexa

Category Peptide
Species Human

AGBL4 fusion protein - Ag22784 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50
Source E. coli -derived, PET28a
Species Human

AGBL4 Blocking Peptide - CBP2822 from Cohesion Biosciences

Category Peptide
Prices $100.00, $300.00
Sizes 1 mg, 5 mg
Species Human

Recombinant Human Cytosolic carboxypeptidase 6(AGBL4) - CSB-YP713349HU CSB-EP713349HU CSB-BP713349HU CSB-MP713349HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CBCP6 Recombinant Protein Antigen - NBP1-91754PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

AGBL4 Peptide, Human - M34GP00369H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Cytosolic carboxypeptidase 6 (AGBL4), Recombinant Protein - MBS1434425 from MyBioSource

Category Protein
Prices $1,290.00, $1,290.00, $1,510.00, $1,510.00, $2,120.00, $2,120.00, $2,585.00, $2,585.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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