AGBL4

Gene Symbol AGBL4
Entrez Gene 84871
Alt Symbol CCP6
Species Human
Gene Type protein-coding
Description ATP/GTP binding protein-like 4
Other Description ATP/GTP-binding protein-like 4|cytosolic carboxypeptidase 6
Swissprots B4DG37 B3KT26 Q5VU57
Accessions EAX06847 Q5VU57 AF075049 AK027348 BAB55053 AK094826 BAG52938 AK294394 BAG57648 AK294633 BAG57812 AK296221 BAG58944 BC035739 BC126383 AAI26384 BC144171 XM_006710986 XP_006711049 XM_011542308 XP_011540610 XM_011542309 XP_011540611 XM_011542310 XP_011540612 XM_011542311 XP_011540613 NM_032785 NP_116174
Function Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5. {ECO:0000250|UniProtKB:Q09LZ8}.
Subcellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q09LZ8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:23085998}. Golgi apparatus {ECO:0000269|PubMed:23085998}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:23085998}. Note=Colocalizes with gamma-tubulin in the centrioles at interphase and dividing cells and with glutamylated tubulin in basal bodies of ciliated cells. {ECO:0000269|PubMed:23085998}.

CCP6 CRISPR/Cas9 KO Plasmid (h) - sc-410212 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 HDR Plasmid (h) - sc-410212-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 Double Nickase Plasmid (h) - sc-410212-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 Double Nickase Plasmid (h2) - sc-410212-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 CRISPR Activation Plasmid (h) - sc-410212-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 CRISPR Activation Plasmid (h2) - sc-410212-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 Lentiviral Activation Particles (h) - sc-410212-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 Lentiviral Activation Particles (h2) - sc-410212-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CCP6 siRNA (h) - sc-88061 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCP6 shRNA Plasmid (h) - sc-88061-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CCP6 shRNA (h) Lentiviral Particles - sc-88061-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU005631 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2939 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2939 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

AGBL4 siRNA (Human) - CRJ3654 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGBL4 - MBS8234203 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AGBL4 (NM_032785.3) - SHH233210 from Creative biogene

Category siRNA
Species Reactivities Human

Human AGBL4 siRNA - orb274155 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGBL4 shRNA Plasmid (Human) - CHJ3654 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AGBL4 miRNA 3'UTR clone - MiUTR3H-13536 from Creative biogene

Species Reactivities Human
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