TRIM11

Gene Symbol TRIM11
Entrez Gene 81559
Alt Symbol BIA1, RNF92
Species Human
Gene Type protein-coding
Description tripartite motif containing 11
Other Description E3 ubiquitin-protein ligase TRIM11|RING finger protein 92|tripartite motif-containing 11|tripartite motif-containing protein 11
Swissprots B3KUS3 Q8NCA6 Q96F44 Q9C022 Q5VSU1 B4DX88 A6NKE2 B2RB82
Accessions EAW69871 Q96F44 AF220125 AAG53498 AF327056 AAM63957 AK074866 BAC11254 AK097825 BAG53535 AK226119 AK301859 BAG63300 AK314539 BAG37129 AL360165 BC011629 AAH11629 BC069227 AAH69227 EU447015 ABZ92544 XM_011544285 XP_011542587 NM_145214 NP_660215
Function E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Ubiquitous.

TRIM11 (H-70) - sc-366347 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TRIM11 (H-70): sc-366347. Western blot analysis of TRIM11 expression in Jurkat (A), HeLa (B), K-562 (C) and MCF7 (D) whole cell lysates.

TRIM11 (P-17) - sc-79759 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TRIM11 (L-15) - sc-79758 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TRIM11 (L-15): sc-79758. Western blot analysis of TRIM11 expression in U-937 whole cell lysate.

Anti-TRIM11 antibody - ab111694 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-TRIM11 antibody (ab111694) at 1/2000 dilution + Jurkat whole cell lysate at 30 µg

Anti-TRIM11 antibody - ab128814 from Abcam

Prices $370.00
Sizes 100 µl
Host Goat
Clonality Polyclonal
Anti-TRIM11 antibody (ab128814) at 0.3 µg/ml + Human spleen lysate in RIPA buffer at 35 µgdeveloped using the ECL technique

Anti-TRIM11 antibody - ab4153 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab4153 (4µg/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.

Anti-TRIM11 antibody - C-terminal - ab171641 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-TRIM11 antibody - C-terminal (ab171641) at 1/100 dilution + HepG2 cell line lysate at 35 µg

Anti-TRIM11 Antibody (aa454-467) - LS-C55618 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-TRIM11 Antibody (aa299-330, Biotin) - LS-C224428 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 Antibody (aa299-330, AP) - LS-C224429 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 Antibody (aa299-330, FITC) - LS-C224431 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 Antibody (aa299-330, APC) - LS-C224430 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 Antibody (aa299-330, Azide-free, HRP) - LS-C224433 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 Antibody (aa299-330) - LS-C325928 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 Antibody (aa299-330, PE) - LS-C224435 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 Antibody (aa383-432) - LS-C135129 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
TRIM11 antibody LS-C135129 Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml.

Anti-TRIM11 Antibody (aa300-329) - LS-C157267 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TRIM11 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-TRIM11 Antibody (aa249-263) IHC-plus™ - LS-B10341 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-TRIM11 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10341 concentration 5 ug/ml.

Trim11 Antibody - NB100-1214 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: Trim11 Antibody [NB100-1214] - Trim11 in human D54 malignant glioma cell line. Image provided by Kaijun Di.

Trim11 Antibody - NBP1-88609 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Trim11 Antibody [NBP1-88609] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

Trim11 Antibody - NBP2-20705 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Trim11 Antibody [NBP2-20705] - Sample (30 ug of whole cell lysate) A: Jurkat 7. 5% SDS PAGE gel, diluted at 1:2000.

RNF92 Polyclonal Antibody - bs-9148R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TRIM11 antibody produced in rabbit - HPA028541 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TRIM11: <B>Cat. No. HPA028541</B>: Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Anti-TRIM11 antibody produced in rabbit - SAB2700615 from Sigma-Aldrich

Prices $326.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TRIM11: <B>Cat. No. SAB2700615</B>: Immunohistochemical analysis of paraffin-embedded Hepatoma, using RNF92 antibody at 1:500 dilution.

ANTI-TRIM11 (C-TERM) antibody produced in rabbit - SAB1303407 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>TRIM11 (C-term): <B>Cat. No. SAB1303407</B>: TRIM11 in Human heart tissue with TRIM11 antibody (C-term) at 25 μg/mL.
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