TRIM11

Gene Symbol TRIM11
Entrez Gene 81559
Alt Symbol BIA1, RNF92
Species Human
Gene Type protein-coding
Description tripartite motif containing 11
Other Description E3 ubiquitin-protein ligase TRIM11|RING finger protein 92|tripartite motif-containing 11|tripartite motif-containing protein 11
Swissprots B3KUS3 Q8NCA6 Q96F44 Q9C022 Q5VSU1 B4DX88 A6NKE2 B2RB82
Accessions EAW69871 Q96F44 AF220125 AAG53498 AF327056 AAM63957 AK074866 BAC11254 AK097825 BAG53535 AK226119 AK301859 BAG63300 AK314539 BAG37129 AL360165 BC011629 AAH11629 BC069227 AAH69227 EU447015 ABZ92544 XM_011544285 XP_011542587 NM_145214 NP_660215
Function E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction
Subcellular Location Cytoplasm. Nucleus.
Tissue Specificity Ubiquitous.

Human-TRIM11-cDNA-Clone - DC03146 from Abgent, a WuXi AppTec company

Prices $272.70
Sizes 10 µg
Species Human
Accession BC011629

TRIM11 - MBS1275134 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC011629

Human TRIM11 cDNA clone(NM_145214.2) - CDFG008926 from Creative Biomart

Species Human
Accession NM_145214.2

human TRIM11 ORF clone - CDCH094816 from Creative Biomart

Species Human
Accession NM_145214

human TRIM11 ORF clone - CDCH094817 from Creative Biomart

Species Human
Accession NM_145214

human TRIM11 ORF clone - CDCH094818 from Creative Biomart

Species Human
Accession NM_145214

human TRIM11 ORF clone - CDCH094819 from Creative Biomart

Species Human
Accession NM_145214

Human TRIM11 ORF Clone(NM_145214.2) - CDCR318270 from Creative Biomart

Species Human
Accession NM_145214.2

Human TRIM11 ORF Clone(NM_145214.2) - CDCR318271 from Creative Biomart

Species Human
Accession NM_145214.2

Human TRIM11 ORF Clone(NM_145214.2) - CDCR318272 from Creative Biomart

Species Human
Accession NM_145214.2

Human TRIM11 ORF Clone(NM_145214.2) - CDCL179585 from Creative Biomart

Species Human
Accession NM_145214.2

Human TRIM11 ORF Clone(NM_145214.2) - CDCL179586 from Creative Biomart

Species Human
Accession NM_145214.2

Human TRIM11 ORF Clone(NM_145214.2) - CDCR318270 from Creative biogene

Species Human

Human TRIM11 ORF Clone (BC011629) - CDCS417002 from Creative biogene

Species Human
Accession Q96F44

Human TRIM11 cDNA Clone(NM_145214.2) - CDFG008926 from Creative biogene

Species Human
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